CD81 Antikörper

Produktnummer ABIN119111

Der Hamster Monoklonal Anti-CD81-Antikörper wurde für FACS, WB, IP, IHC (fro) und EIA validiert. Er ist geeignet, CD81 in Proben von Maus zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für CD81 Antikörper (ABIN119111)

Target: CD81

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser CD81 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Klon: Eat2

Produktdetails anti-CD81 Antikörper

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: 38C13, murine B cell line. Spleen cells from immunised Armenian hamsters were fused with cells of the mouse PX3-Ag.8.653 myeloma cell line.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1/50 - 1/100, use 10 μL of the suggested working dilution to label 106 cells in 100 μL. Immunoprecipitation. Immunohistochemistry on frozen sections. ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Referenzen für anti-CD81 Antikörper (ABIN119111)

Blumenthal, Giebel, Ummanni, Schlüter, Endlich, Endlich: "Morphology and migration of podocytes are affected by CD151 levels." in: American journal of physiology. Renal physiology, Vol. 302, Issue 10, pp. F1265-77, (2012) (PubMed).

Details zu CD81

Target: CD81

Andere Bezeichnung: CD81 / TAPA1

Hintergrund: TAPA1, or CD81, is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell surface proteins that are characterised by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TAPA1 is a cell surface glycoprotein that is known to complex with integrins. It appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. TAPA1 gene is localized in the tumor suppressor gene region and thus it is a candidate gene for malignancies.Synonyms: 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1

Gen-ID: 10090

UniProt: P35762

Pathways: Inositol Metabolic Process, Hepatitis C