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HLA B7 Antikörper (PE)

Dieses Anti-HLA B7-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von HLA B7 in FACS. Geeignet für Human.
Produktnummer ABIN118935

Kurzübersicht für HLA B7 Antikörper (PE) (ABIN118935)

Target

Alle HLA B7 Antikörper anzeigen
HLA B7 (HLA Class I B7 Alpha (HLA B7))

Reaktivität

  • 16
  • 6
  • 2
  • 2
  • 2
Human

Wirt

  • 14
  • 2
Maus

Klonalität

  • 14
  • 2
Monoklonal

Konjugat

  • 9
  • 5
  • 2
Dieser HLA B7 Antikörper ist konjugiert mit PE

Applikation

  • 12
  • 3
  • 2
  • 1
  • 1
Flow Cytometry (FACS)

Klon

BB7-1
  • Spezifität

    This antibody binds to the HLA-B7 antigen and does not cross-react with HLA-B27 or other related HLA antigens. It can be used to distinguish true HLA-B27 positives from false HLA-B27 positives (i.e. HLA-B7 positive) in the investigation of such diseases as ankylosing spondylitis and anterior uveitis.

    Aufreinigung

    Affinity chromatography on Protein G

    Immunogen

    Papain solubilized HLA-B7 antigen.

    Isotyp

    IgG1
  • Applikationshinweise

    Flow cytometry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Rekonstitution

    Restore with 1 mL distilled water.

    Buffer

    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    On receipt store the antibody (in aliquots) at -20 °C.
  • Target

    HLA B7 (HLA Class I B7 Alpha (HLA B7))

    Hintergrund

    HLA B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Hundreds of HLA B alleles have been described.Synonyms: B-7 alpha chain, HLA class I histocompatibility antigen, HLAB, MHC class I antigen B7

    Gen-ID

    3106

    NCBI Accession

    NP_005505

    UniProt

    P01889

    Pathways

    Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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