CD7 Antikörper (Biotin)

Produktnummer ABIN118543

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD7 in FACS und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CD7 Antikörper (Biotin) (ABIN118543)

Target: CD7

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD7 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: LT7

Produktdetails anti-CD7 Antikörper (Biotin)

Spezifität: This antibody is a single chain cell surface glycoprotein of 40 kDa, expressed by T cells, NK cells and thymocytes. CD7 is also expressed by tumour cells in some cases of acute myeloid leukaemia.

Aufreinigung: Affinity chromatography on Protein A

Immunogen: Normal human peripheral blood lymphocytes. Spleen cells from immunised BALB/c mice were fused with cells of the X63.653 mouse myeloma cell line.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % Bovine Serum Albumin as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CD7

Target: CD7

Andere Bezeichnung: CD7

Hintergrund: CD7 is a 40 kDa transmembrane, single-chain glycoprotein, which is a member of the immunoglobulin superfamily. CD7 is expressed by the majority of thymocytes and mature T cells, NK cells and pre-B cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. The function of CD7 is not yet known although cross-linking of CD7 with antibodies induces a T cell transmembrane calcium flux and CD7 expression is induced by ionomycin. The CD7 Molecule has been reported to be the receptor for the IgM-Fc portion (FcR mu) on the surface of T cells.Synonyms: GP40, Leu-9, T-cell leukemia antigen, TP41

Gen-ID: 924

NCBI Accession: NP_006128

UniProt: P09564

Pathways: Cell-Cell Junction Organization