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CD16 Antikörper

CD16 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal LNK16 unconjugated

Produktnummer ABIN118542

Datenblatt (PDF)

Target Alle CD16 Antikörper anzeigen

CD16
Reaktivität
145

26

21

21

21

9

9

8

8

4

3

3

2

2

2

2

2

2

2

2

2

2
Human
Wirt
127

25

19

1
Maus
Passende Sekundärantikörper
Klonalität
147

23

1
Monoklonal
Konjugat
63

19

14

14

9

5

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD16 Antikörper ist unkonjugiert
Applikation
139

34

29

26

26

25

21

18

6

6

5

3

3

3

2

2

1

1

1

1
Flow Cytometry (FACS), Immunoprecipitation (IP)

Spezifität

This antibody recognizes CD16. This antibody has been reported to block the binding of IgG to the CD16 Molecule. (4)

Aufreinigung

Ion Exchange Chromatography

Immunogen

Normal Human peripheral blood granulocytes. Remarks: Spleen cells from immunised BALB/c mice were fused with cells of the mouse X63.653 myeloma cell line.

Klon

LNK16

Isotyp

IgG1

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Applikationshinweise

Flow cytometry: Use 10 μL of 1/10-1/20 diluted antibody to label 10^6 cells or 100 μL human whole blood. Immunoprecipitation. Does not work in Immunohistochemistry on Frozen and Paraffin Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target

CD16

Andere Bezeichnung

CD16 (CD16 Produkte)

Hintergrund

CD16 is a 50-65kD cell surface molecule which exists in two forms, a transmembranous form expressed by NK cells and some T cells, and a phosphatidylinositol linked form expressed by granulocytes. CD16 is a low affinity receptor for IgG (FcR III), and is an important receptor mediating ADCC by NK cells.Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A

Gen-ID

2214

NCBI Accession

NP_000560

UniProt

P08637

Pathways

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process