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CD4 Antikörper

Dieser Maus Monoklonal Antikörper erkennt spezifisch CD4 in FACS, IHC (fro) und Func. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN118486

Kurzübersicht für CD4 Antikörper (ABIN118486)

Target

Alle CD4 Antikörper anzeigen
CD4

Reaktivität

  • 430
  • 264
  • 134
  • 48
  • 30
  • 24
  • 22
  • 20
  • 17
  • 12
  • 11
  • 11
  • 11
  • 10
  • 10
  • 10
  • 9
  • 9
  • 9
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 444
  • 169
  • 161
  • 5
  • 5
  • 3
  • 1
  • 1
Maus

Klonalität

  • 644
  • 137
  • 5
Monoklonal

Konjugat

  • 245
  • 75
  • 62
  • 53
  • 42
  • 16
  • 12
  • 11
  • 11
  • 11
  • 10
  • 10
  • 8
  • 7
  • 7
  • 6
  • 6
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
Dieser CD4 Antikörper ist unkonjugiert

Applikation

  • 646
  • 220
  • 166
  • 119
  • 103
  • 93
  • 72
  • 60
  • 54
  • 40
  • 39
  • 30
  • 17
  • 12
  • 12
  • 9
  • 8
  • 7
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Klon

RPA-T4
  • Spezifität

    This antibody recognises CD4. Epitope mapping studies have shown that clone RPA-T4 recognises an epitope within domain 1 of the extracellular region of the CD4 Molecule. Clone RPA-T4 has been reported to block gp120-CD4 interaction and inhibit syncytium formation (See Voehringer, D. et al. for details).

    Aufreinigung

    Affinity Chromatography on Protein G

    Endotoxin-Niveau

    Low Endotoxin

    Immunogen

    Human PHA blasts. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.

    Isotyp

    IgG1
  • Applikationshinweise

    Functional Assays. Flow Cytometry: 1/50 - 1/100, Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Immunohistochemistry on frozen sections: 1/200 - 1/2000. Recommended Positive Control: Human lymphatic tissue
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    PBS, pH 7.4, None, None

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Upon receipt, store undiluted (in aliquots) at -20 °C.
  • Target

    CD4

    Andere Bezeichnung

    CD4

    Hintergrund

    CD4 is a 55kD cell surface glycoprotein that is expressed primarily on a subpopulation of T lymphocytes and on peripheral blood monocytes and tissue macrophages.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

    Gen-ID

    920

    NCBI Accession

    NP_000607

    UniProt

    P01730

    Pathways

    T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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