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CD4 Antikörper

CD4 Reaktivität: Human FACS, IHC (fro), Func Wirt: Maus Monoclonal RPA-T4 unconjugated

Produktnummer ABIN118486

Datenblatt (PDF)

Target Alle CD4 Antikörper anzeigen

CD4
Reaktivität
359

232

126

48

24

22

20

19

17

10

10

10

10

10

10

9

9

9

9

5

4

2

2

1

1

1

1

1
Human
Wirt
383

147

137

3

3

1
Maus
Passende Sekundärantikörper
Klonalität
528

138

5
Monoklonal
Konjugat
213

73

64

49

36

16

13

12

11

10

9

9

9

9

8

8

7

6

5

5

4

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2
Dieser CD4 Antikörper ist unkonjugiert
Applikation
535

203

141

118

98

76

73

42

39

36

31

30

17

10

9

9

8

7

6

6

5

4

4

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Spezifität

This antibody recognises CD4. Epitope mapping studies have shown that clone RPA-T4 recognises an epitope within domain 1 of the extracellular region of the CD4 Molecule. Clone RPA-T4 has been reported to block gp120-CD4 interaction and inhibit syncytium formation (See Voehringer, D. et al. for details).

Aufreinigung

Affinity Chromatography on Protein G

Endotoxin-Niveau

Low Endotoxin

Immunogen

Human PHA blasts. Spleen cells from immunised BALB/c mice were fused with cells of the mouse NS1 myeloma cell line.

Klon

RPA-T4

Isotyp

IgG1

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anti-CD4 (CD4) antibody
CD4 Reaktivität: Human, Maus, Ratte, Huhn, Affe, Hund, Schwein, Cat, Rind (Kuh), Kaninchen, Schaf, Meerschweinchen, Ziege, Pferd, Avian, Esel, Hamster WB Wirt: Ziege Polyclonal unconjugated

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anti-CD4 (CD4) (AA 301-400) antibody
CD4 Reaktivität: Human, Maus, Ratte FACS, WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

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CD4 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-241 PE

anti-CD4 (CD4) antibody (PE)
CD4 Reaktivität: Ratte FACS Wirt: Maus Monoclonal OX-35 PE

anti-CD4 (CD4) (AA 26-200) antibody
CD4 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Functional Assays. Flow Cytometry: 1/50 - 1/100, Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Immunohistochemistry on frozen sections: 1/200 - 1/2000. Recommended Positive Control: Human lymphatic tissue
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

PBS, pH 7.4, None, None

Handhabung

Avoid repeated freezing and thawing.

Lagerung

-20 °C

Informationen zur Lagerung

Upon receipt, store undiluted (in aliquots) at -20 °C.
Target

CD4

Andere Bezeichnung

CD4 (CD4 Produkte)

Hintergrund

CD4 is a 55kD cell surface glycoprotein that is expressed primarily on a subpopulation of T lymphocytes and on peripheral blood monocytes and tissue macrophages.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

Gen-ID

920

NCBI Accession

NP_000607

UniProt

P01730

Pathways

T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events