CD8 Antikörper
-
- Target Alle CD8 Antikörper anzeigen
- CD8
-
Reaktivität
- Maus
-
Wirt
- Ratte
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser CD8 Antikörper ist unkonjugiert
-
Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)
- Spezifität
- This antibody recognises mouse Ly2.1 and Ly2.2 cells, reacting with the CD8 alpha chain (non polymorphic). It is weakly cytotoxic.
- Aufreinigung
- Affinity chromatography on Protein A
- Immunogen
- T cell clone, C6. Spleen cells from immunised SD rats were fused with cells of the NSO mouse myeloma cell line.
- Klon
- KT15
- Isotyp
- IgG2a
- Top Product
- Discover our top product CD8 Primärantikörper
-
-
- Applikationshinweise
-
Flow cytometry: 1/10 - 1/50, use 10 μL of the suggested working dilution to label 10^6 cellsin 100 μL. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Konzentration
- 1.0 mg/mL
- Buffer
- PBs, pH 7.4 containing 0.09 % Sodium Azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Target
- CD8
- Andere Bezeichnung
- CD8 (CD8 Produkte)
- Hintergrund
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
- Gen-ID
- 12525
- NCBI Accession
- NP_001074579
- UniProt
- P01731
-