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- Target Alle CD8 Antikörper anzeigen
- CD8
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD8 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Marke
- BD Pharmingen™
- Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- Sterilität
- 0.2 μm filtered
- Endotoxin-Niveau
- Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
- Klon
- RPA-T8
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD8 Primärantikörper
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anti-CD8 (CD8) (AA 51-150) antibody
CD8 Reaktivität: Human, Maus, Ratte FACS, IHC (fro), WB, ELISA, IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-CD8 (CD8) antibody (PE)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 PE
anti-CD8 (CD8) (AA 22-187) antibodyCD8 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-CD8 (CD8) antibodyCD8 Reaktivität: Human FACS, IP, MS Wirt: Maus Monoclonal MEM-31 unconjugated
anti-CD8 (CD8) antibody (FITC)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 FITC
anti-CD8 (CD8) antibody (Biotin)CD8 Reaktivität: Human FACS, IP Wirt: Maus Monoclonal MEM-31 Biotin
anti-CD8 (CD8) antibodyCD8 Reaktivität: Human IHC, IP, WB, ELISA Wirt: Kaninchen Monoclonal 3C3 unconjugated Recombinant Antibody
anti-CD8 (CD8) antibody (PerCP)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 PerCP
anti-CD8 (CD8) antibody (APC)CD8 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-31 APC
anti-CD8 (CD8) antibody (PE)CD8 Reaktivität: Cat FACS Wirt: Maus Monoclonal fCD8 PE
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/mL
- Buffer
- No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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- Target
- CD8
- Andere Bezeichnung
- CD8 (CD8 Produkte)
- Hintergrund
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The RPA-T8 monoclonal antibody specifically binds to CD8 alpha (CD8alpha). CD8alpha is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. CD8alpha is expressed by the majority of thymocytes, by subpopulations of alphabeta T cells and gammadelta T cells and by some NK cells. Cell surface CD8alpha is expressed either as a disulfide-linked homodimer (CD8alphaalpha) or as a heterodimer (CD8alphabeta) when disulfide-bonded to a CD8 beta chain (CD8beta). CD8-positive alphabeta T cells coexpress both CD8alphaalpha homodimers and CD8alphabeta heterodimers whereas some gammadelta T cells and NK cells express CD8alphaalpha homodimers. CD8 plays important roles in T cell activation and selection. The extracellular IgSF domain of CD8alpha binds to a non-polymorphic determinant on HLA class I molecules (alpha3 domain) and enables CD8 to function as a co-receptor with MHC class I-restricted TCR during T cell recognition of antigen. The cytoplasmic domain of CD8alpha associates with Lck, a Src family protein tyrosine kinase that is involved in intracellular signaling. The RPA-T8 and HIT8a (Cat. No. 555337) monoclonal antibodies are not cross-blocking.
Synonyms: CD8alpha, CD8A, CD8 alpha, Leu2, MAL, T8, p32
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