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ICAM2 Antikörper

ICAM2 Reaktivität: Maus FACS, IP, IHC (fro), BR, IHC (f) Wirt: Ratte Monoclonal 3C4 unconjugated
Produktnummer ABIN1177303
  • Target Alle ICAM2 Antikörper anzeigen
    ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
    Reaktivität
    • 68
    • 31
    • 20
    Maus
    Wirt
    • 52
    • 20
    • 18
    Ratte
    Klonalität
    • 52
    • 37
    Monoklonal
    Konjugat
    • 45
    • 9
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ICAM2 Antikörper ist unkonjugiert
    Applikation
    • 56
    • 51
    • 24
    • 24
    • 19
    • 13
    • 13
    • 13
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Marke
    BD Pharmingen™
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau
    Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
    Immunogen
    Transfected Cell Line
    Klon
    3C4
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product ICAM2 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.0 mg/mL
    Buffer
    No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • Gerwin, Gonzalo, Lloyd, Coyle, Reiss, Banu, Wang, Xu, Avraham, Engelhardt, Springer, Gutierrez-Ramos: "Prolonged eosinophil accumulation in allergic lung interstitium of ICAM-2 deficient mice results in extended hyperresponsiveness." in: Immunity, Vol. 10, Issue 1, pp. 9-19, (1999) (PubMed).

    Xu, Bickford, Luther, Carpenito, Takei, Springer: "Characterization of murine intercellular adhesion molecule-2." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 156, Issue 12, pp. 4909-14, (1996) (PubMed).

  • Target
    ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))
    Andere Bezeichnung
    CD102 (ICAM2 Produkte)
    Hintergrund
    The 3C4 (mIC2/4) antibody reacts with the mouse ICAM-2 (CD102) cell surface glycoprotein, a ligand for LFA-1. CD102 is constitutively expressed on endothelial cells, T and B lymphocytes, and alveolar walls. It is also expressed on a variety of leukocyte cell lines. CD102 does not appear to be involved in the development of hematopoietic cells. In a model for allergic asthma, endothelial CD102 mediates the transmigration of eosinophils (but not lymphocytes, monocytes, or macrophages) into the airway lumen. The 3C4 (mIC2/4) antibody blocks interactions between ICAM-2 and LFA-1.
    Synonyms: ICAM-2
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