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ICAM2 Antikörper
ICAM2
Reaktivität: Maus
FACS, IP, IHC (fro), BR, IHC (f)
Wirt: Ratte
Monoclonal
3C4
unconjugated
Produktnummer ABIN1177303
Produktdetails anti-ICAM2 Antikörper
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Target
Alle ICAM2 Antikörper anzeigen
ICAM2
(Intercellular Adhesion Molecule 2 (ICAM2))
Reaktivität
Alle Reaktivitäten für ICAM2 Antikörper
Maus
Wirt
Alle Wirte für ICAM2 Antikörper
Ratte
Klonalität
Alle Klonalitäten für ICAM2 Antikörper
Monoklonal
Konjugat
Alle Konjugate für ICAM2 Antikörper
Dieser ICAM2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für ICAM2 Antikörper
Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
Marke
BD Pharmingen™
Aufreinigung
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Sterilität
0.2 μm filtered
Endotoxin-Niveau
Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.
Immunogen
Transfected Cell Line
Klon
3C4
Isotyp
IgG2a kappa
Top Product
Discover our top product ICAM2 Primärantikörper
Alternativen
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Anwendungsinformationen
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Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1.0 mg/mL
Buffer
No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.
Konservierungsmittel
Azide free
Lagerung
4 °C
Informationen zur Lagerung
Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Referenzen für anti-ICAM2 Antikörper (ABIN1177303)
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Gerwin, Gonzalo, Lloyd, Coyle, Reiss, Banu, Wang, Xu, Avraham, Engelhardt, Springer, Gutierrez-Ramos : "Prolonged eosinophil accumulation in allergic lung interstitium of ICAM-2 deficient mice results in extended hyperresponsiveness. " in: Immunity , Vol. 10 , Issue 1 , pp. 9-19 , (1999 ) (PubMed ).
Xu, Bickford, Luther, Carpenito, Takei, Springer : "Characterization of murine intercellular adhesion molecule-2. " in: Journal of immunology (Baltimore, Md. : 1950) , Vol. 156 , Issue 12 , pp. 4909-14 , (1996 ) (PubMed ).
Details zu ICAM2
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Target
ICAM2
(Intercellular Adhesion Molecule 2 (ICAM2))
Andere Bezeichnung
CD102 (ICAM2 Produkte )
Hintergrund
The 3C4 (mIC2/4) antibody reacts with the mouse ICAM-2 (CD102) cell surface glycoprotein, a ligand for LFA-1. CD102 is constitutively expressed on endothelial cells, T and B lymphocytes, and alveolar walls. It is also expressed on a variety of leukocyte cell lines. CD102 does not appear to be involved in the development of hematopoietic cells. In a model for allergic asthma, endothelial CD102 mediates the transmigration of eosinophils (but not lymphocytes, monocytes, or macrophages) into the airway lumen. The 3C4 (mIC2/4) antibody blocks interactions between ICAM-2 and LFA-1. Synonyms: ICAM-2
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