Ezrin Antikörper (pTyr353) (Alexa Fluor 488)
(2 Referenzen)Kurzübersicht für Ezrin Antikörper (pTyr353) (Alexa Fluor 488) (ABIN1177059)
Target
Alle Ezrin (EZR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pTyr353
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Marke
- BD Phosflow™
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Aufreinigung
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Immunogen
- Phosphorylated Human Ezrin Peptide
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Isotyp
- IgG1 kappa
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anti-Ezrin (EZR) (AA 292-464) antibody
EZR Reaktivität: Human, Maus, Affe WB, ELISA, ICC, FACS Wirt: Maus Monoclonal 6F1A9 unconjugated
anti-Ezrin (EZR) (AA 1-295) antibodyEZR Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Ezrin (EZR) (AA 1-586) antibodyEZR Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Ezrin (EZR) (pTyr478) antibodyEZR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Ezrin (EZR) (AA 1-586) antibodyEZR Reaktivität: Human WB, ELISA, IHC (p), PLA Wirt: Maus Monoclonal 1E11 unconjugated
anti-Ezrin (EZR) antibodyEZR Reaktivität: Human WB, IHC, StM Wirt: Maus Monoclonal CPTC-Ezrin-1 unconjugated
anti-Ezrin (EZR) (pTyr353) antibodyEZR Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Ezrin (EZR) (AA 350-470) antibodyEZR Reaktivität: Human WB, IP, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Ezrin (EZR) (AA 1-251) antibodyEZR Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Ezrin (EZR) (AA 455-586) antibodyEZR Reaktivität: Human, Ratte WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Probenmenge
- 20 μL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- The antibody was conjugated to Alexa Fluor® 488 under optimum conditions, and unreacted Alexa Fluor® 488 was removed. Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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: "Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 13, pp. 7300-5, (1999) (PubMed).
: "Identification of the two major epidermal growth factor-induced tyrosine phosphorylation sites in the microvillar core protein ezrin." in: The Journal of biological chemistry, Vol. 267, Issue 27, pp. 19258-65, (1992) (PubMed).
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: "Ezrin, a plasma membrane-microfilament linker, signals cell survival through the phosphatidylinositol 3-kinase/Akt pathway." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 13, pp. 7300-5, (1999) (PubMed).
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- Ezrin (EZR)
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Andere Bezeichnung
- Ezrin
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Hintergrund
- Ezrin is a member of the ERM (ezrin-radixin-moesin) family of proteins that function as crosslinkers between the actin cytoskeleton and the plasma membrane. Ezrin is a substrate for the tyrosine kinase epidermal (EGF) and hepatocyte growth factor (HGF) receptors. Upon EGF or HGF stimulation, ezrin is phosphorylated on tyrosine 353 (Y353), which is required for its interaction with phosphatidylinositol 3 kinase p85 subunit and activation of Akt. The I66-386 monoclonal antibody recognizes the phosphorylated Y353 of human ezrin.
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Pathways
- Maintenance of Protein Location
Target
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