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CD16 Antikörper

Name: CD16 Antikörper
SKU: ABIN1176930
Price: 350.65 EUR
Availability: InStock

CD16 Reaktivität: Human FACS Wirt: Maus Monoclonal 3G8 unconjugated

FACS

1 image

(1 reference)

Produktnummer ABIN1176930

Datenblatt (PDF)

Target Alle CD16 Antikörper anzeigen

CD16
Reaktivität
145

26

21

21

21

9

9

8

8

4

3

3

2

2

2

2

2

2

2

2

2

2
Human
Wirt
127

25

19

1
Maus
Passende Sekundärantikörper
Klonalität
147

23

1
Monoklonal
Konjugat
63

19

14

14

9

5

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD16 Antikörper ist unkonjugiert
Applikation
139

34

29

26

26

25

21

18

6

6

5

3

3

3

2

2

1

1

1

1
Flow Cytometry (FACS)

Marke

BD Pharmingen™

Aufreinigung

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Sterilität

0.2 μm filtered

Endotoxin-Niveau

Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Immunogen

Human polymorphonuclear leukocytes

Klon

3G8

Isotyp

IgG1 kappa

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Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1.0 mg/mL

Buffer

No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Konservierungsmittel

Azide free

Lagerung

4 °C

Informationen zur Lagerung

Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Wirthmueller, Kurosaki, Murakami, Ravetch: "Signal transduction by Fc gamma RIII (CD16) is mediated through the gamma chain." in: The Journal of experimental medicine, Vol. 175, Issue 5, pp. 1381-90, (1992) (PubMed).
Target

CD16

Andere Bezeichnung

CD16 (CD16 Produkte)

Hintergrund

The 3G8 monoclonal antibody specifically binds to the 50-65 kDa transmembrane form of the IgG Fc Receptor (FcgammaRIII), a human NK-cell-associated antigen. CD16 is expressed on NK cells as well as macrophages and granulocytes. Reports indicate that CD16 plays a role in signal transduction and NK cell activation. The 3G8 antibody blocks the binding of soluble immune complexes to granulocytes.
Synonyms: FcRIII, Fc-gamma RIII, FCG3, FCGR3, FCGRIII, FcgammaRIII, IGFR3

Pathways

Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process