CTRP6 Antikörper (Globular Domain, Globular Domain-less)

Produktnummer ABIN1169274

Produktdetails anti-CTRP6 Antikörper

Target: CTRP6 (C1QTNF6) (Complement C1q Tumor Necrosis Factor-Related Protein 6 (C1QTNF6))

Bindungsspezifität: Globular Domain, Globular Domain-less

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CTRP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Recognizes the N-terminal half of human CTRP6 full-length protein. Detects bands of ~16 kDa and ~32 kDa by Western blot.

Kreuzreaktivität: Human

Aufreinigung: Purified from concentrated hybridoma tissue culture supernatant.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human CTRP6 (globular domain-less).

Klon: 256-E

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu CTRP6

Target: CTRP6 (C1QTNF6) (Complement C1q Tumor Necrosis Factor-Related Protein 6 (C1QTNF6))

Andere Bezeichnung: CTRP6 (C1QTNF6 Produkte)

Synonyme: MGC148634 antikoerper, CTFP6 antikoerper, CTRP6 antikoerper, ZACRP6 antikoerper, 2810036M19Rik antikoerper, Ctrp6 antikoerper, C1q and TNF related 6 antikoerper, C1q and tumor necrosis factor related protein 6 antikoerper, C1QTNF6 antikoerper, C1qtnf6 antikoerper

Hintergrund: CTRP6 mediates the phosphorylation of AMPK and acetyl-CoA carboxylase (ACC) in skeletal muscle cells, subsequently mediating glycogen accumulation and fatty acid oxidation. It induces the expression of the potent anti-inflammatory cytokine IL-10 in macrophages. CTRP6 may be a potential serum marker for hepatocellular carcinoma, contributing to tumor angiogenesis by activating the Akt pathway. CTRP6 was also shown to be associated with obesity, type 1 diabetes mellitus (T1D), vitiligo (depigmentation of the skin) and ASFV (African Swine Fever Virus). CTRP6 forms homotrimers and higher-order oligomers and it may also form heteromeric complexes with CTRP1. May be involved in kidney inflammation.

UniProt: Q9BXI9