NQO1 Antikörper

Produktnummer ABIN1169221

Dieser Maus Monoklonal Antikörper detektiert spezifisch NQO1 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für NQO1 Antikörper (ABIN1169221)

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NQO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: Skiny-1

Produktdetails anti-NQO1 Antikörper

Verwendungszweck: anti-NQO1 (human), mAb (Skiny-1)

Spezifität: Recognizes human NQO1. Detects a band of ~32 kDa by Western blot.

Produktmerkmale: Monoclonal Antibody. Recognizes human NQO1. Detects a band of ~32 kDa by Western blot. Isotype: Mouse IgG2akappa. Clone: Skiny-1. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body's protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer's disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human NQO1.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Konservierungsmittel: Without preservative

Handhabung: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu NQO1

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Andere Bezeichnung: NQO1

Hintergrund:

Alternate Names/Synonyms: NAD(P)H Dehydrogenase (Quinine) 1 (NQO1), Quinone Reductase 1 (QR1), DT-Diaphorase (DTD), Azoreductase, Phylloquinone Reductase, Menadione Reductase, Dioxin-inducible 1, Disphorase-4 (DIA4), NAD(P)H:Quinone Oxireductase, NAD(P)H:Quinone Oxidoreductase 1

Product Description: NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body's protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer's disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.

UniProt: Q3B792