ADIPOQ Antikörper
Kurzübersicht für ADIPOQ Antikörper (ABIN1169211)
Target
Alle ADIPOQ Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- anti-Adiponectin (human), mAb (HADI 773)
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Spezifität
- Recognizes human adiponectin. Detects a band of ~30 kDa by Western blot. Cross-reactivity with other species not tested.
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Kreuzreaktivität (Details)
- Cross-reactivity with other species not tested.
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Produktmerkmale
- Monoclonal Antibody. Recognizes human adiponectin. Detects a band of ~30 kDa by Western blot. Cross-reactivity with other species not tested. Isotype: Mouse IgG1kappa. Clone: HADI 773. Applications: ELISA, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte differentiation. Plasma levels are reduced in obese humans, and low levels are associated with insulin-resistance. Treatment of db/db mice with TZD increased ACRP30 levels.
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Sterilität
- 0.2 μm filtered
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Immunogen
- Recombinant human adiponectin.
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Isotyp
- IgG1 kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4.
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Konservierungsmittel
- Without preservative
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Handhabung
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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Haltbarkeit
- 12 months
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: "The expression of adiponectin receptors Adipo-R1 and Adipo-R2 is associated with an intestinal histotype and longer survival in gastric carcinoma." in: Journal of clinical pathology, Vol. 62, Issue 8, pp. 705-9, (2009) (PubMed).
: "Renin receptor expression in human adipose tissue." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 292, Issue 1, pp. R274-82, (2007) (PubMed).
: "Adiponectin expression in human fetal tissues during mid- and late gestation." in: The Journal of clinical endocrinology and metabolism, Vol. 90, Issue 4, pp. 2397-402, (2005) (PubMed).
: "Genetic association study of adiponectin polymorphisms with risk of Type 2 diabetes mellitus in Korean population." in: Diabetic medicine : a journal of the British Diabetic Association, Vol. 22, Issue 5, pp. 569-75, (2005) (PubMed).
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- ADIPOQ (Adiponectin (ADIPOQ))
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Andere Bezeichnung
- Adiponectin
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Hintergrund
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Alternate Names/Synonyms: ACRP30, AdipoQ, apM1, GBP28, Adipocyte Complement Related Protein of 30 kDa
Product Description: ACRP30 was identified as a novel adipocyte-specific synthesized and secreted protein with structural resemblance to complement factor C1q. Like adipsin, ACRP30 secretion is induced ~10-fold during adipocyte differentiation. Plasma levels are reduced in obese humans, and low levels are associated with insulin-resistance. Treatment of db/db mice with TZD increased ACRP30 levels.
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UniProt
- Q15848
Target
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