DLK1 Antikörper (Extracellular Domain)

Produktnummer ABIN1169189

Der Kaninchen Polyklonal Anti-DLK1-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, DLK1 in Proben von Human zu detektieren.

Kurzübersicht für DLK1 Antikörper (Extracellular Domain) (ABIN1169189)

Target: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-DLK1 Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: Recognizes human DLK1. Detects a band of ~42 kDa by Western blot.

Kreuzreaktivität: Human

Kreuzreaktivität (Details): Weakly cross-reacts with mouse Dlk1.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human DLK1 (extracellular domain).

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Haltbarkeit: 6 months

Details zu DLK1

Target: DLK1 (delta-Like 1 Homolog (Drosophila) (DLK1))

Andere Bezeichnung: DLK1

Hintergrund: The transmembrane and secreted protein delta-like 1 homolog (DLK1, Protein delta homolog 1, Preadipocyte factor 1, Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.

UniProt: P80370