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IL-33 Antikörper

IL33 Reaktivität: Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1169164
  • Target Alle IL-33 (IL33) Antikörper anzeigen
    IL-33 (IL33) (Interleukin 33 (IL33))
    Reaktivität
    • 83
    • 47
    • 39
    • 9
    • 1
    Maus
    Wirt
    • 101
    • 27
    • 8
    • 3
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 113
    • 30
    Polyklonal
    Konjugat
    • 72
    • 23
    • 13
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL-33 Antikörper ist unkonjugiert
    Applikation
    • 84
    • 67
    • 36
    • 29
    • 19
    • 15
    • 14
    • 14
    • 13
    • 11
    • 9
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    Recognizes mouse IL-33. Detects a band of ~18 kDa by Western blot.
    Kreuzreaktivität
    Maus
    Keine Kreuzreaktivität
    Human
    Kreuzreaktivität (Details)
    Does not cross-react with human IL-33.
    Sterilität
    0.2 μm filtered
    Immunogen
    Recombinant mouse IL-33.
    Top Product
    Discover our top product IL33 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Haltbarkeit
    6 months
  • Hayakawa, Hayakawa, Kume, Tominaga: "Soluble ST2 blocks interleukin-33 signaling in allergic airway inflammation." in: The Journal of biological chemistry, Vol. 282, Issue 36, pp. 26369-80, (2007) (PubMed).

  • Target
    IL-33 (IL33) (Interleukin 33 (IL33))
    Andere Bezeichnung
    IL-33 (IL33 Produkte)
    Synonyme
    IL33 antikoerper, C9orf26 antikoerper, DVS27 antikoerper, IL1F11 antikoerper, NF-HEV antikoerper, NFEHEV antikoerper, RP11-575C20.2 antikoerper, 9230117N10Rik antikoerper, Il-33 antikoerper, Il1f11 antikoerper, RGD1311155 antikoerper, interleukin 33 antikoerper, IL33 antikoerper, Il33 antikoerper
    Hintergrund
    Interleukin-33 (IL-33, HF-NEV, IL-1F11), a member of the IL-1 family of cytokines, is expressed by many cell types following pro-inflammatory stimulation and is thought to be released on cell lysis. The 30 kDa human IL33 is converted by CASP1 to a 18 kDa protein. IL33 binds to and signals through ST2 (IL1R1) and its stimulation recruits MYD88, IRAK, IRAK4, and TRAF6, followed by phosphorylation of ERK1(MAPK3)/ERK2(MAPK1), p38(MAPK14), and JNK. The ability of IL-33 to target numerous immune cell types, like Th2-like cells, mast cells, and B1 cells, and to induce cytokine and chemokine production underlines its potential in influencing the outcome of a wide range of diseases, such as arthritis, asthma, atopic allergy & anaphylaxis, cardiovascular disease/atherosclerosis, nervous system diseases, and sepsis.
    UniProt
    Q8BVZ5
    Pathways
    Production of Molecular Mediator of Immune Response
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