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IGF-like family receptor 1 (IGFLR1) (AA 23-154) Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch in WB und FACS. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN1169119

Kurzübersicht für IGF-like family receptor 1 (IGFLR1) (AA 23-154) Antikörper (ABIN1169119)

Target

Alle IGF-like family receptor 1 (IGFLR1) Antikörper anzeigen
IGF-like family receptor 1 (IGFLR1)

Reaktivität

Human

Wirt

  • 4
  • 1
Kaninchen

Klonalität

  • 5
Polyklonal

Konjugat

  • 5
Unkonjugiert

Applikation

  • 5
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 2
    • 1
    • 1
    AA 23-154

    Spezifität

    Recognizes human IGFLR1.

    Kreuzreaktivität

    Human

    Keine Kreuzreaktivität

    Maus

    Kreuzreaktivität (Details)

    Does not recognize mouse IGFLR1.

    Immunogen

    Recombinant human IGFLR1 (aa 23-154).
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    In PBS containing 10 % glycerol and 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.

    Haltbarkeit

    12 months
  • Target

    IGF-like family receptor 1 (IGFLR1)

    Andere Bezeichnung

    IGFLR1

    Hintergrund

    Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL). mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. Mouse IGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149). Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNFR family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.

    UniProt

    Q9H665
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