Stearoyl-Coenzyme A Desaturase 1 (SCD1) (AA 21-33) Antikörper

Produktnummer ABIN1169094

Dieses Anti--Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von in WB und ELISA. Geeignet für Maus.

Kurzübersicht für Stearoyl-Coenzyme A Desaturase 1 (SCD1) (AA 21-33) Antikörper (ABIN1169094)

Target: Stearoyl-Coenzyme A Desaturase 1 (SCD1)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails

Bindungsspezifität: AA 21-33

Spezifität: Recognizes mouse SCD1. Detects a band of ~41 kDa by Western Blot.

Kreuzreaktivität: Maus

Sterilität: 0.2 μm filtered

Immunogen: Synthetic peptide corresponding to aa 21-33 (A21PPSGNEREKVKT33) of mouse SCD1.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Haltbarkeit: 6 months

Antigendetails

Target: Stearoyl-Coenzyme A Desaturase 1 (SCD1)

Andere Bezeichnung: Stearoyl-CoA Desaturase-1

Hintergrund: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme in lipogenesis. The enzyme is constitutively expressed in adipose tissue and is induced in liver in response to fat free, high carbohydrate diet. Several SCD isoforms (SCD1, -2, and -3) exist in the mouse. Mice with a targeted disruption of the SCD1 isoform had reduced body adiposity, increased insulin sensitivity, and resistance to diet-induced weight gain. The protection from obesity involved increased energy expenditure and increased oxygen consumption. SCD1 deficiency shows activation of lipid oxidation in addition to reduced triglyceride synthesis and storage.

UniProt: P13516

Pathways: Brown Fat Cell Differentiation