CRNN Antikörper (AA 259-274)

Produktnummer ABIN1169072

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-CRNN Antikörper wird verwendet zum Nachweis von CRNN in Proben von Human. Er wurde validiert für WB und IHC.

Kurzübersicht für CRNN Antikörper (AA 259-274) (ABIN1169072)

Target: CRNN (Cornulin (CRNN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRNN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CRNN Antikörper

Bindungsspezifität: AA 259-274

Verwendungszweck: anti-Cornulin (human), pAb (SZ1229)

Spezifität: Recognizes human cornulin. Detects a band of ~70 kDa by Western blot.

Produktmerkmale: Polyclonal Antibody. Recognizes human cornulin. Detects a band of ~70 kDa by Western blot. Source: Rabbit. Applications: IHC, WB. Liquid. In PBS containing 1 % BSA and 0.01 % sodium azide. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines. It attenuates deoxycholic acid (DCA)-induced apoptotic cell death and the release of calcium. In overexpressed oral squamous carcinoma cell lines, cornulin negatively regulates cell proliferation by the induction of G1 arrest.

Immunogen: Synthetic peptide corresponding to aa 259-274 (E259ATNDQNRGTETHGQG274) of human cornulin.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: In PBS containing 1 % BSA and 0.01 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Referenzen für anti-CRNN Antikörper (ABIN1169072)

Contzler, Favre, Huber, Hohl: "Cornulin, a new member of the "fused gene" family, is expressed during epidermal differentiation." in: The Journal of investigative dermatology, Vol. 124, Issue 5, pp. 990-7, (2005) (PubMed).

Details zu CRNN

Target: CRNN (Cornulin (CRNN))

Andere Bezeichnung: Cornulin

Hintergrund:

Alternate Names/Synonyms: Tumor Related Protein, C1orf10 Gene Product, Chromosome 1 Open Reading Frame 10 Gene Product

Product Description: Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines. It attenuates deoxycholic acid (DCA)-induced apoptotic cell death and the release of calcium. In overexpressed oral squamous carcinoma cell lines, cornulin negatively regulates cell proliferation by the induction of G1 arrest.

UniProt: Q9UBG3