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SIRT6 Antikörper

SIRT6 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal S6R82-2 unconjugated
Produktnummer ABIN1169069
  • Target Alle SIRT6 Antikörper anzeigen
    SIRT6 (Sirtuin 6 (SIRT6))
    Reaktivität
    • 90
    • 31
    • 16
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 87
    • 11
    • 2
    Maus
    Klonalität
    • 83
    • 17
    Monoklonal
    Konjugat
    • 51
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SIRT6 Antikörper ist unkonjugiert
    Applikation
    • 81
    • 39
    • 36
    • 14
    • 14
    • 11
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    Recognizes human sirtuin 6. Detects a band of ~47 kDa by Western blot.
    Kreuzreaktivität
    Human
    Sterilität
    0.2 μm filtered
    Immunogen
    Recombinant human sirtuin 6.
    Klon
    S6R82-2
    Isotyp
    IgG2b
    Top Product
    Discover our top product SIRT6 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Haltbarkeit
    12 months
  • Target
    SIRT6 (Sirtuin 6 (SIRT6))
    Andere Bezeichnung
    Sirtuin 6 (SIRT6 Produkte)
    Synonyme
    2810449N18Rik antikoerper, AI043036 antikoerper, Sir2l6 antikoerper, SIR2L6 antikoerper, zgc:86729 antikoerper, sirtuin 6 antikoerper, sirtuin 6 S homeolog antikoerper, Sirt6 antikoerper, SIRT6 antikoerper, sirt6.S antikoerper, sirt6 antikoerper
    Hintergrund
    Sirtuin 6 (SIRT6) is a NAD-dependent protein deacetylase with activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. It is required for genomic stability and for normal IGF1 serum levels and normal glucose homeostasis. It also regulates cellular senescence and apoptosis. Unlike most sirtuins, SIRT6 preferentially removes long-chain fatty-acyl, rather than acetyl, protein modifications. This activity regulates secretion of the inflammation-associated protein TNF-alpha.
    UniProt
    Q8N6T7
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