SIRT6 Antikörper
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- Target Alle SIRT6 Antikörper anzeigen
- SIRT6 (Sirtuin 6 (SIRT6))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser SIRT6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Spezifität
- Recognizes human sirtuin 6. Detects a band of ~47 kDa by Western blot.
- Kreuzreaktivität
- Human
- Sterilität
- 0.2 μm filtered
- Immunogen
- Recombinant human sirtuin 6.
- Klon
- S6R82-2
- Isotyp
- IgG2b
- Top Product
- Discover our top product SIRT6 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
- Konservierungsmittel
- Without preservative
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - Haltbarkeit
- 12 months
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- Target
- SIRT6 (Sirtuin 6 (SIRT6))
- Andere Bezeichnung
- Sirtuin 6 (SIRT6 Produkte)
- Synonyme
- 2810449N18Rik antikoerper, AI043036 antikoerper, Sir2l6 antikoerper, SIR2L6 antikoerper, zgc:86729 antikoerper, sirtuin 6 antikoerper, sirtuin 6 S homeolog antikoerper, Sirt6 antikoerper, SIRT6 antikoerper, sirt6.S antikoerper, sirt6 antikoerper
- Hintergrund
- Sirtuin 6 (SIRT6) is a NAD-dependent protein deacetylase with activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. It is required for genomic stability and for normal IGF1 serum levels and normal glucose homeostasis. It also regulates cellular senescence and apoptosis. Unlike most sirtuins, SIRT6 preferentially removes long-chain fatty-acyl, rather than acetyl, protein modifications. This activity regulates secretion of the inflammation-associated protein TNF-alpha.
- UniProt
- Q8N6T7
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