TRIB3 Antikörper (AA 112-125)
Kurzübersicht für TRIB3 Antikörper (AA 112-125) (ABIN1169021)
Target
Alle TRIB3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 112-125
-
Spezifität
- Recognizes human TRB-3. Detects a band of ~28 kDa by Western blot (predicted 39 kDa).
-
Kreuzreaktivität
- Human
-
Sterilität
- 0.2 μm filtered
-
Immunogen
- Synthetic peptide corresponding to aa 112-125 (A112RLPPHKHVARPTE125) of human TRB-3.
-
-
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 56-145) antibody
TRIB3 Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 3D7 unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 56-145) antibodyTRIB3 Reaktivität: Human WB, ELISA, IF, RNAi Wirt: Maus Monoclonal 1H2 unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) antibodyKD Validated TRIB3 Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB4690 unconjugated Recombinant Antibody
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 15-45), (N-Term) antibodyTRIB3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB4069-RB4070 unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 152-325) antibodyTRIB3 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (C-Term) antibodyTRIB3 Reaktivität: Human IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 1-358) antibodyTRIB3 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 1-358) antibodyTRIB3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (AA 315-332) antibodyTRIB3 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Tribbles Homolog 3 (Drosophila) (TRIB3) (N-Term) antibodyTRIB3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
-
Konservierungsmittel
- Without preservative
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. -
Haltbarkeit
- 6 months
-
-
- TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
-
Andere Bezeichnung
- TRB-3
-
Hintergrund
- Tribbles homolog 3 (TRB-3) is a pseudokinase, shown to act as a potent negative regulator of PPARgamma, a master regulator of adipocyte differentiation, and to control adipogenesis. It disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. It interacts also with the NF-kappaB transactivator p65 RELA. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells.
-
UniProt
- Q96RU7
-
Pathways
- Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Lipid Metabolism by PPARalpha
Target
-
