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TRIB3 Antikörper (AA 112-125)

TRIB3 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1169021
  • Target Alle TRIB3 Antikörper anzeigen
    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
    Bindungsspezifität
    • 16
    • 12
    • 11
    • 8
    • 8
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 112-125
    Reaktivität
    • 68
    • 28
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 75
    • 5
    Kaninchen
    Klonalität
    • 75
    • 5
    Polyklonal
    Konjugat
    • 41
    • 7
    • 6
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRIB3 Antikörper ist unkonjugiert
    Applikation
    • 57
    • 43
    • 14
    • 13
    • 13
    • 13
    • 12
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Spezifität
    Recognizes human TRB-3. Detects a band of ~28 kDa by Western blot (predicted 39 kDa).
    Kreuzreaktivität
    Human
    Sterilität
    0.2 μm filtered
    Immunogen
    Synthetic peptide corresponding to aa 112-125 (A112RLPPHKHVARPTE125) of human TRB-3.
    Top Product
    Discover our top product TRIB3 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    Konservierungsmittel
    Without preservative
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Haltbarkeit
    6 months
  • Target
    TRIB3 (Tribbles Homolog 3 (Drosophila) (TRIB3))
    Andere Bezeichnung
    TRB-3 (TRIB3 Produkte)
    Synonyme
    zgc:76966 antikoerper, TRIB3 antikoerper, C20orf97 antikoerper, NIPK antikoerper, SINK antikoerper, SKIP3 antikoerper, TRB3 antikoerper, Ifld2 antikoerper, Nipk antikoerper, TRB-3 antikoerper, Trb3 antikoerper, tribbles pseudokinase 3 antikoerper, trib3 antikoerper, TRIB3 antikoerper, Trib3 antikoerper
    Hintergrund
    Tribbles homolog 3 (TRB-3) is a pseudokinase, shown to act as a potent negative regulator of PPARgamma, a master regulator of adipocyte differentiation, and to control adipogenesis. It disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. It interacts also with the NF-kappaB transactivator p65 RELA. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells.
    UniProt
    Q96RU7
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Lipid Metabolism by PPARalpha
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