NOTCH2 Antikörper (Biotin)

Produktnummer ABIN1169005

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch NOTCH2 in FACS. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für NOTCH2 Antikörper (Biotin) (ABIN1169005)

Target: NOTCH2 (Notch 2 (NOTCH2))

Reaktivität: Human, Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser NOTCH2 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Klon: 16F11

Produktdetails anti-NOTCH2 Antikörper (Biotin)

Spezifität: Recognizes human and mouse endogenous Notch-2 receptor.

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified from concentrated hybridoma tissue culture supernatant.

Reinheit: >95 % (SDS-PAGE)

Immunogen: Recombinant mouse Notch2:Fc .

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: In PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu NOTCH2

Target: NOTCH2 (Notch 2 (NOTCH2))

Andere Bezeichnung: Notch2

Hintergrund: Notch signaling pathway regulates many different cell fate decisions in both vertebrate and invertebrate species. There are 5 canonical Notch ligands in mammals: Jagged-1, Jagged-2, DLL1, DLL3 and DLL4. These can bind to the four Notch receptors Notch 1-4. It is important for pattern formation during development such as neurogenesis, angiogenesis or myogenesis and regulates T cell development and stem cell maintenance. Notch signaling is also involved in cellular processes through-out adulthood. Signaling via Notch occurs between neighbouring cells and both the receptor and its ligands are transmembrane proteins.

UniProt: O35516

Pathways: Notch Signalweg, Stem Cell Maintenance