CCL3L1 Antikörper

Produktnummer ABIN116429

Der Ziege Polyklonal Anti-CCL3L1-Antikörper wurde für WB und EIA validiert. Er ist geeignet, CCL3L1 in Proben von Human zu detektieren.

Kurzübersicht für CCL3L1 Antikörper (ABIN116429)

Target: CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser CCL3L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CCL3L1 Antikörper

Aufreinigung: Affinity chromatography employing immobilized hLD78-Beta matrix.

Immunogen: Highly pure (>98%) recombinant hLC78-beta

Anwendungsinformationen

Applikationshinweise: Neutralization. ELISA: To detect hLD78-Beta by direct ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant hLD78-Beta. Western Blot: To detect hLD78-Beta by Western Blot analysis this antibody can be used ata concentration of 0.1- 0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hLD78-Beta is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile water to a concentration of > 0.2 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Details zu CCL3L1

Target: CCL3L1 (Chemokine (C-C Motif) Ligand 3-Like 1 (CCL3L1))

Andere Bezeichnung: LD78 beta / CCL3L1

Hintergrund: LD78 belongs to the intercrine beta (chemokine CC) family. It is closely related to MIP-1 alpha. This protein binds to several chemokine receptors including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, binding of this protein to CCR5 inhibits HIV entry, and LD78 beta has been shown to exhibit potent activity in HIV suppression assays. The copy number of the LD78 gene varies among individuals, most individuals have 1-6 copies in the diploid genome, although rare individuals have zero or more than six copies. The gene encodes a 93 amino acid preprotein, the mature protein contains 70 amino acids.Synonyms: C-C motif chemokine 3-like 1, D17S1718, G0/G1 switch regulatory protein 19-2, G0S19-2, SCYA3L1, Small-inducible cytokine A3-like 1, Tonsillar lymphocyte LD78 beta protein

Gen-ID: 414062

NCBI Accession: NP_001001437

UniProt: P16619

Pathways: Cellular Response to Molecule of Bacterial Origin