CXCL11 Antikörper

Produktnummer ABIN116297

Der Kaninchen Polyklonal Anti-CXCL11-Antikörper wurde für WB, EIA und Func validiert. Er ist geeignet, CXCL11 in Proben von Human zu detektieren.

Kurzübersicht für CXCL11 Antikörper (ABIN116297)

Target: CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCL11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)

Produktdetails anti-CXCL11 Antikörper

Spezifität: This antibody reacts with Human I-TAC

Aufreinigung: Affinity chromatography.

Immunogen: Highly pure (>98%) recombinant hI-TAC.

Anwendungsinformationen

Applikationshinweise: Neutralization: To yield one-half maximal inhibition [NND50] of the biological activity ofhI-TAC (100 ng/mL), a concentration of 7.0-8.0 μg/mL of this antibody is required. ELISA: To detect hI-TAC by direct ELISA (using 100l/well antibody solution) aconcentration of at least 0.5g/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with compatible secondary reagents, allows the detection of0.2-0.4 ng/well of recombinant hI-TAC. Western Blot: To detect hI-TAC by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hI-TAC is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing. Centrifuge vial prior to opening!

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Details zu CXCL11

Target: CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))

Andere Bezeichnung: CXCL11 / ITAC

Hintergrund: This member of the the intercrine alpha (chemokine CxC) family is chemotactive for interleukin-activated T cells but not unstimulated T cells, neutrophils or monocytes. It induces calcium release in activated T cells and binds to CXCR3. It may play an important role in CNS diseases which involve T cell recruitment and in skin immune responses. It is expressed at high levels in peripheral blood leukocytes, pancreas and liver astrocytes and at moderate levels in thymus, spleen and lung. It is induced by interferon gamma and interferon beta.Synonyms: Beta-R1, C-X-C motif chemokine 11, H174, I-TAC, IP-9, Interferon-gamma-inducible protein 9, Interferon-inducible T-cell alpha chemoattractant, SCYB11, SCYB9B, Small-inducible cytokine B11

Gen-ID: 6373

NCBI Accession: NP_005400

UniProt: O14625