CXCL7 Antikörper

Produktnummer ABIN116187

Produktdetails anti-CXCL7 Antikörper

Target: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCL7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)

Spezifität: This antibody reacts with Human Neutrophil Activating Protein-2 (hNAP-2).

Aufreinigung: Affinity Chromatography using an immobilized Human NAP-2 matrix

Immunogen: Highly pure (>98%) E.coli derived recombinant Human NAP-2.

Anwendungsinformationen

Applikationshinweise: Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhNAP-2 (50.0 ng/mL), a concentration of 1.75-3.0 μg/mL of this antibody is required. ELISA: To detect hNAP-2 by direct ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof recombinant hNAP-2. Western Blot: To detect hNAP-2 by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hNAP-2 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing. Centrifuge vial prior to opening!

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Details zu CXCL7

Target: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Andere Bezeichnung: NAP2 / PPBP / CXCL7 (PPBP Produkte)

Synonyme: 2400003M24Rik antikoerper, AI854500 antikoerper, CTAP3 antikoerper, CTAPIII antikoerper, Cxcl7 antikoerper, LA-PF4 antikoerper, LDGF antikoerper, MDGF antikoerper, NAP-2 antikoerper, NAP-2-L1 antikoerper, Scyb7 antikoerper, TGB antikoerper, TGB1 antikoerper, THBGB1 antikoerper, b-TG1 antikoerper, beta-TG antikoerper, B-TG1 antikoerper, Beta-TG antikoerper, CTAP-III antikoerper, CXCL7 antikoerper, PBP antikoerper, SCYB7 antikoerper, TC1 antikoerper, TC2 antikoerper, THBGB antikoerper, Nap-2 antikoerper, CTAPIII/NAP-2 antikoerper, Platelet basic protein antikoerper, pro-platelet basic protein antikoerper, scyb7 antikoerper, Ppbp antikoerper, PPBP antikoerper

Hintergrund: NAP2 is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and sythesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.Synonyms: C-X-C motif chemokine 7, CTAP3, Leukocyte-derived growth factor, Macrophage-derived growth factor, SCYB7, Small-inducible cytokine B7, TGB1, THBGB1

Gen-ID: 5473

NCBI Accession: NP_002695

UniProt: P02775