CXCL10 Antikörper (Biotin)
Kurzübersicht für CXCL10 Antikörper (Biotin) (ABIN116121)
Target
Alle CXCL10 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Affinity chromatography.
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Immunogen
- Highly pure (>98%) recombinant hIP-10 (human IP-10).
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Applikationshinweise
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ELISA: To detect hIP-10 by direct ELISA (using 100 l/well antibody solution) this antibodycan be used at a concentration of 0.15 - 0.30 μg/mL. Used in conjunction with compatiblesecondary reagents, allows the detection of at least 0.2 ng/well of recombinant hIP-10. Western Blot: To detect hIP-10 by Western Blot analysis this antibody can be used at aconcentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hIP-10 is 1.5 - 3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Rekonstitution
- Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.
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Buffer
- PBS, pH 7.2 without preservatives.
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Konservierungsmittel
- Without preservative
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Handhabung
- Avoid repeated freezing and thawing. Centrifuge vial prior to opening!
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody at 4-8 °C for one month or at -20 °C for longer.
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- CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
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Andere Bezeichnung
- CXCL10 / IP-10
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Hintergrund
- Interferon-gamma-inducible 10 kD protein (IP-10), is a CXC chemokine with chemoattractant properties for CD4-positive T cells and inhibits early normal and leukemic hemopoietic progenitor proliferation. IP-10 is produced by a wide variety of cell types ranging from neutrophils and monocytes to hepatocytes, endothelial cells and keratinocytes. The cytokine is reported to be involved in a scala of inflammatory pathologies such as HIV encephalitis, cutaneous T cell lymphoma, chronic hepatitis and acute anterior uveitis. Various observations strongly suggest a role for the CXC chemokines IL-8 and IP-10 in the regulation of angiogenic activity in cancer and in idiopathic pulmonary fibrosis.Synonyms: 10 kDa interferon-gamma-induced protein, C-X-C motif chemokine 10, Gamma-IP10, INP10, SCYB10, Small-inducible cytokine B10
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Gen-ID
- 9606
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UniProt
- P02778
Target
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