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CCL1 Antikörper

CCL1 Reaktivität: Human WB, EIA, Func Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN116047
  • Target Alle CCL1 Antikörper anzeigen
    CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))
    Reaktivität
    • 36
    • 5
    Human
    Wirt
    • 30
    • 6
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 33
    • 6
    Polyklonal
    Konjugat
    • 23
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCL1 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 13
    • 13
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
    Spezifität
    This antibody reacts with human I-309.
    Aufreinigung
    Affinity chromatography.
    Immunogen
    Highly pure (>98%) recombinant hI-309.
    Top Product
    Discover our top product CCL1 Primärantikörper
  • Applikationshinweise
    Neutralization. ELISA: To detect hI-309 by direct ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant hI-309. Western Blot: To detect hI-309 by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hI-309 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    PBS, pH 7.2 without preservatives.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • Target
    CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))
    Andere Bezeichnung
    CCL1 / I-309 (CCL1 Produkte)
    Synonyme
    I-309 antikoerper, P500 antikoerper, SCYA1 antikoerper, SISe antikoerper, TCA3 antikoerper, BF534335 antikoerper, Scya1 antikoerper, Tca-3 antikoerper, CCLi6 antikoerper, chemokine antikoerper, C-C motif chemokine ligand 1 antikoerper, chemokine (C-C motif) ligand 1 antikoerper, CCL1 antikoerper, Ccl1 antikoerper
    Hintergrund
    I-309 is a member of the C-C, or beta chemokine class. Other chemokines in this group include MIP1 alpha, MIP1 beta, RANTES, MCP1/2/3/4, mouse JE, 1 - 2 μg/mL antibody detects 20 and mouse MARC, eotaxin, HCC1 and C10. These chemokines act primarily as chemoattractants and activate monocytes, dendritic cells, T lymphocytes, natural killer cells, B lymphocytes, basophils and eosinophils. I-309 was originally identified by subtractive hybridization as a transcript that was present in a gamma/delta T cell line but not in EBVtransformed B cells. I-309 is a chemoattractant for monocytes, but not for neutrophils. IP-10 is an approximately 8.5 kD polypeptide of 73 amino acids. The precursor form of human I-309 consists of 96 amino acids. To generate the mature I-309, the precursor cleaves its hydrophobic signal peptide. Human I-309 is thought to be a homologue of the mouse TCA3, and shows 42 % amino acid homology to mouse TCA3.Synonyms: C-C motif chemokine 1, CCL-1, SCYA1, Small-inducible cytokine A1, T lymphocyte-secreted protein I-309
    Gen-ID
    6346
    NCBI Accession
    NP_002972
    UniProt
    P22362
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