CXCL2 Antikörper

Produktnummer ABIN115945

Produktdetails anti-CXCL2 Antikörper

Target: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognises Rat GROβ/MIP-2.

Aufreinigung: Affinity chromatography.

Immunogen: highly pure (>98%) recombinant rat GRO/b/MIP-2

Anwendungsinformationen

Applikationshinweise: Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of Rat GROβ/MIP-2(100 ng/mL), a concentration of 3.0-5.0 μg/mL of this antibody is requiredELISA: (Indirect): To detect Rat GROβ/MIP-2 by indirect ELISA (using 100 μL/well antibody solution)a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with compatible secondary reagents, allows the detection of atleast 0.2- 0.4 ng/well of recombinant Rat GROβ/MIP-2. (Sandwich): To detect Rat GROβ/MIP-2 by sandwich ELISA (using 100 μL/well antibodysolution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with Biotinylated Anti-Rat GROβ/MIP-2 (PP032B) as adetection antibody, allows the detection of at least 0.2-0.4 ng/well of recombinant RatGROβ/MIP-2. Western Blot: To detect Rat GROβ/MIP-2 by Western Blot analysis this antibody can be used at a

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing. Centrifuge vial prior to opening!

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Details zu CXCL2

Target: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Andere Bezeichnung: CXCL2 / MIP2A (CXCL2 Produkte)

Synonyme: CINC-2a antikoerper, GRO2 antikoerper, GROb antikoerper, MGSA-b antikoerper, MIP-2a antikoerper, MIP2 antikoerper, MIP2A antikoerper, SCYB2 antikoerper, GRO3 antikoerper, Gro2 antikoerper, MIP-2 antikoerper, Mgsa-b antikoerper, Mip2 antikoerper, Scyb antikoerper, Scyb2 antikoerper, Mip-2 antikoerper, GROB antikoerper, MIP-2alpha antikoerper, C-X-C motif chemokine ligand 2 antikoerper, chemokine (C-X-C motif) ligand 2 antikoerper, CXCL2 antikoerper, Cxcl2 antikoerper

Hintergrund: GRO beta is a member of the CXC, or chemokine class. It contains the ELR domain immediately preceding the first cysteine residue near the amino terminus. Other chemokines in this group include IL8, GRO alpha/beta/gamma, mouse KC, ENA78, GCP2, PBP/CTAPIII/beta TG/NAP2. These chemokines act primarily on neutrophils as chemoattractants and activators, including neutrophil degradation with release of myloperoxidase and other enzymes. GRO beta was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. GRO beta is an approximately 8 kDa polypeptide of 73 amino acids. The precursor form of GRO beta consists of 100 amino acids. To generate the mature GRO beta, the precursor cleaves its amino terminal 27 amino acids. GRO beta shows 60 % amino acid homology to human GRO alpha and GRO gamma.Synonyms: C-X-C motif chemokine 2, GRO2, GROB, Gro-beta, Growth-regulated protein beta, MIP-2A, MIP2-alpha, Macrophage inflammatory protein 2-alpha, SCYB2

Gen-ID: 114105

NCBI Accession: NP_446099

UniProt: P30348

Pathways: Cellular Response to Molecule of Bacterial Origin