CCL22 Antikörper

Produktnummer ABIN115780

Produktdetails anti-CCL22 Antikörper

Target: CCL22 (Chemokine (C-C Motif) Ligand 22 (CCL22))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCL22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)

Spezifität: Recognises Human Macrophage Derived Chemokine (MDC)

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: highly pure (>98%) recombinant Human MDC

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: In a sandwich ELISA (assuming 100 μL/well), a concentration of 2-4 μg/mL of thisantibody will detect at least 100 pg/mL of recombinant Human MDC when used withbiotinylated antigen affinity purified anti-Human MDC antibody (cat. PP1049B) as thedetection antibody at a concentration of at least 1 μg/mL. Western Blot: To detect Human MDC by Western Blot analysis this antibody can be used ata concentration of 0.25-0.50 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant hMDC is 0.25-0.50 ng/lane, undernon-reducing conditions. Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhMIG (100 ng/mL), a concentration of 5.0-10.0 μg/mL of this antibody is required.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile water to a concentration of 1.0 mg/mL.

Buffer: PBS without preservatives

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Details zu CCL22

Target: CCL22 (Chemokine (C-C Motif) Ligand 22 (CCL22))

Andere Bezeichnung: MDC / CCL22 (CCL22 Produkte)

Synonyme: ABCD-1 antikoerper, DC/B-CK antikoerper, MDC antikoerper, SCYA22 antikoerper, STCP-1 antikoerper, DCBCK antikoerper, Scya22 antikoerper, Mdc antikoerper, CCL22 antikoerper, C-C motif chemokine ligand 22 antikoerper, chemokine (C-C motif) ligand 22 antikoerper, CCL22 antikoerper, Ccl22 antikoerper

Hintergrund: The MDC gene is one of several Cys-Cys (CC) cytokine genes which are clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by MDC displays chemotactic activity for natural killer cells, chronically activated T lymphocytes, monocytes and dendritic cells. It has no chemoattractant activity for eosinophils, neutrophils and resting T lymphocytes and also displays a mild activity for primary activated T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.Synonyms: C-C motif chemokine 22, CC chemokine STCP-1, Macrophage-derived chemokine, SCYA22, Small-inducible cytokine A22, Stimulated T-cell chemotactic protein 1

Gen-ID: 6367

NCBI Accession: NP_002981

UniProt: O00626