PROX1 Antikörper (C-Term)

Produktnummer ABIN115694

Produktdetails anti-PROX1 Antikörper

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PROX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects Prox-1 in the nucleus of lymphatic endothelial cells.

Kreuzreaktivität (Details): Species reactivity (expected):Rat.
Species reactivity (tested):Human, Mouse.

Aufreinigung: Protein A Chromatography

Immunogen: Highly pure (>95%) recombinant Human, highly conserved C-terminal part of Prox1 (homeo domain and prospero domain) derived from E.coli.

Anwendungsinformationen

Applikationshinweise: Western blot (1 - 5 μg/mL). Immunofluorescence (1: 750 - 1: 1000). Immunohistochemistry: the antibody works well with paraffin sections. A boiling step isrecommended when staining paraffin-embedded tissues.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: 5 mM PBS, pH 7.4 without stabilizer or preservative

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu PROX1

Target: PROX1 (Prospero Homeobox 1 (PROX1))

Andere Bezeichnung: PROX-1 (PROX1 Produkte)

Synonyme: xprox1 antikoerper, prospero antikoerper, PROX1 antikoerper, LOC100232600 antikoerper, A230003G05Rik antikoerper, prox1 antikoerper, zgc:111888 antikoerper, prospero homeobox 1 antikoerper, prospero homeobox 1 L homeolog antikoerper, prospero homeobox 1a antikoerper, PROX1 antikoerper, prox1.L antikoerper, prox1 antikoerper, Prox1 antikoerper, prox1a antikoerper

Hintergrund: Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells.Synonyms: Homeobox prospero-like protein PROX1, PROX1, Prospero homeobox protein 1

Gen-ID: 5629

NCBI Accession: NP_002754

UniProt: Q92786

Pathways: Stem Cell Maintenance, Regulation of Muscle Cell Differentiation