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LYVE1 Antikörper (AA 24-232)

LYVE1 Reaktivität: Human WB, FACS, IHC (fro), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN115662
  • Target Alle LYVE1 Antikörper anzeigen
    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
    Bindungsspezifität
    • 13
    • 12
    • 9
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-232
    Reaktivität
    • 75
    • 57
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 83
    • 6
    • 4
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 84
    • 12
    Polyklonal
    Konjugat
    • 52
    • 11
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LYVE1 Antikörper ist unkonjugiert
    Applikation
    • 84
    • 40
    • 38
    • 20
    • 18
    • 9
    • 9
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    Spezifität
    The antibody recognizes LYVE-1.
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Protein A Chromatography (+ his tag depleted)
    Immunogen
    Recombinant Human soluble LYVE-1 (24-232) produced in insect cells. Remarks: The recombinant soluble LYVE-1 consists of amino acid 24 (Ser) to 232 (Gly) and is fused to a C-terminal His-tag (6xHis).
    Top Product
    Discover our top product LYVE1 Primärantikörper
  • Applikationshinweise
    ELISA (1-15 μg/mL). Western blot (1-2 μg/mL). FACS analysis (3-20 μg/mL). Immunohistochemistry on Frozen Sections (6-30 μg/mL). Please Note: For use on Paraffin Embedded Sections the affinity-purified antibody(ABIN115663) is recommended.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore in sterile water to a concentration of > 0.5 mg/mL.
    Buffer
    PBS, pH 7.4 without preservatives or stabilizers
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    The lyophilized IgG is stable at 2-8 °C for one month or at -20 °C for one year from despatch. When reconstituted the antibody is stable for six weeks at 2-8 °C and at -20 °C for longer. Aliquot to
    Haltbarkeit
    12 months
  • Spyridonidou, Fousteris, Antonia, Chatzianastasiou, Papapetropoulos, Nikolaropoulos: "Tricyclic indole and dihydroindole derivatives as new inhibitors of soluble guanylate cyclase." in: Bioorganic & medicinal chemistry letters, Vol. 19, Issue 16, pp. 4810-3, (2009) (PubMed).

    Kimura, Miyashita, Suzuki, Kobayashi, Watanabe, Sonoda, Ohta, Fujiwara, Shimosegawa, Sato: "Distinctive localization and opposed roles of vasohibin-1 and vasohibin-2 in the regulation of angiogenesis." in: Blood, Vol. 113, Issue 19, pp. 4810-8, (2009) (PubMed).

    Geissler, Dashkevich, Fischer, Fries, Kuhn-Régnier, Addicks, Mehlhorn, Bloch: "First year changes of myocardial lymphatic endothelial markers in heart transplant recipients." in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 29, Issue 5, pp. 767-71, (2006) (PubMed).

  • Target
    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
    Andere Bezeichnung
    LYVE-1 (LYVE1 Produkte)
    Synonyme
    LYVE1 antikoerper, XLKD1 antikoerper, CRSBP-1 antikoerper, HAR antikoerper, LYVE-1 antikoerper, 1200012G08Rik antikoerper, Crsbp-1 antikoerper, Lyve-1 antikoerper, Xlkd1 antikoerper, lymphatic vessel endothelial hyaluronic receptor 1a antikoerper, lymphatic vessel endothelial hyaluronan receptor 1 antikoerper, lyve1a antikoerper, LYVE1 antikoerper, Lyve1 antikoerper
    Hintergrund
    LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosamino-glycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41 % similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 Molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 Molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.Synonyms: CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, LYVE1, Lymphatic vessel endothelial hyaluronic acid receptor 1, XLKD1
    Gen-ID
    10894
    NCBI Accession
    NP_006682
    UniProt
    Q9Y5Y7
    Pathways
    Glycosaminoglycan Metabolic Process
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