Periostin Antikörper

Produktnummer ABIN115513

Produktdetails anti-Periostin Antikörper

Target: Periostin (POSTN)

Reaktivität: Human, Maus, Ratte, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Periostin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Sequenz: MGHHHHHHHH HHSSGHIEGR HMRNNHYDKI LAHSRIRGRD QGPNVCALQQ ILGTKKKYFS TCKNWYKKSI CGQKTTVLYE CCPGYMRMEG MKGCPAVLPI DHVYGTLGIV GATTTQRYSD ASKLREEIEG KGSFTYFAPS NEAWDNLDSD IRRGLESNVN VELLNALHSH MINKRMLTKD LKNGMIIPSM YNNLGLFINH YPNGVVTVNC ARIIHGNQIA TNGVVHVIDR VLTQIGTSIQ DFIEAEDDLS SFRAAAITSD ILEALGRDGH FTLFAPTNEA FEKLPRGVLE RFMGDKVASE ALMKYHILNT LQCSESIMGG AVFETLEGNT IEIGCDGDSI TVNGIKMVNK KDIVTNNGVI HLIDQVLIPD SAKQVIELAG KQQTTFTDLV AQLGLASALR PDGEYTLLAP VNNAFSDDTL SMVQRLLKLI LQNHILKVKV GLNELYNGQI LETIGGKQLR VFVYRTAVCI ENSCMEKGSK QGRNGAIHIF REIIKPAEKS LHEKLKQDKR FSTFLSLLEA ADLKELLTQP GDWTLFVPTN DAFKGMTSEE KEILIRDKNA LQNIILYHLT PGVFIGKGFE PGVTNILKTT QGSKIFLKEV NDTLLVNELK SKESDIMTTN GVIHVVDKLL YPADTPVGND QLLEILNKLI KYIQIKFVRG STFKEIPVTV Y Remarks: The immunizati on antigen (75 kDa) is a protein containing 648 amino acids of recombinan t Human OSF-2 and 23 amino acids, N-Terminal HisTag and Xa - cleavage site (highlighte d). The antigen contains amino acid residues 22 to 669 of the Human OSF-2 precursor. The antigen includes all four fasciclin domains of OSF-2.

Spezifität: The antibody recognizes OSF-2.

Aufreinigung: Immunoaffinity Chromatography on Immoblized Recombinant Human OSF2

Immunogen: Recombinant Human OSF-2 Source of Antigen: E. coli.

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot (0.1-1 μg/mL). Immunohistochemistry on Paraffin (1/100-1/5,000) and Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Add 0.05 mL of deionized water and let the lyophilized pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.

Buffer: 0.05 M Phosphate Buffer, 0.1 M NaCl, pH 7.2 without preservatives

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Stable the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Periostin

Target: Periostin (POSTN)

Andere Bezeichnung: Periostin (POSTN Produkte)

Synonyme: fa99h07 antikoerper, pn antikoerper, postn antikoerper, wu:fa99h07 antikoerper, wu:fc70f09 antikoerper, zgc:153873 antikoerper, LOC100008945 antikoerper, osf-2 antikoerper, pdlpostn antikoerper, periostin antikoerper, OSF-2 antikoerper, OSF2 antikoerper, PDLPOSTN antikoerper, PN antikoerper, RP11-412K4.1 antikoerper, A630052E07Rik antikoerper, AI747096 antikoerper, Osf2 antikoerper, PLF antikoerper, peri antikoerper, Plf antikoerper, periostin antikoerper, periostin, osteoblast specific factor b antikoerper, periostin, osteoblast specific factor antikoerper, POSTN antikoerper, postnb antikoerper, postn antikoerper, Postn antikoerper

Hintergrund: Periostin is a disulfide linked 90 kDa 811 amno acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta-1(TGFbeta1) and bone morphogenetic protein (BMP)-2. OSF-2 has a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain and a C-terminal domain. The fourfold repeated domain of OSF-2 shows homology with the insect protein fasciclin. Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart.Synonyms: OSF-2, OSF2, Osteoblast-specific factor 2, PN, POSTN

Gen-ID: 10631

NCBI Accession: NP_001129406

UniProt: Q15063