CST3 Antikörper

Produktnummer ABIN115497

Dieses Anti-CST3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CST3 in WB und EIA. Geeignet für Human.

Kurzübersicht für CST3 Antikörper (ABIN115497)

Target: CST3 (Cystatin C (CST3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CST3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-CST3 Antikörper

Spezifität: The antibody was raised in rabbits by immunization with the Cystatin C.

Aufreinigung: Immunoaffinity chromatography

Immunogen: Cystatin C from human urine

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 0.1 mL of deionized water

Konzentration: 1.0 mg/mL

Buffer: 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE

Konservierungsmittel: Azide free

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.

Haltbarkeit: 6 months

Details zu CST3

Target: CST3 (Cystatin C (CST3))

Andere Bezeichnung: Cystatin-C

Hintergrund: Cystatin C is a non-glycosilated basic single-chain protein consisting of 120 amino acids with a molecular weight of 13.36 kDa and is characterized by two disulfide bonds in the carboxy-terminal region. It belongs to the cystatins superfamilly which inactivates lysosomal cysteine proteinases, e.g. cathepsin B, H,.K, L and S. Imbalance between Cystatin C and cysteine proteinases is associated with inflammation, renal failure, cancer, Alzheimers disease, multiple sclerosis and hereditary Cystatin C amyloid angiopathy. Its increased level has been found in patients with autoimune diseases, with colorectal tumors and in patients on dyalisis. Serum Cystatin C seems to be better marker of glomerular filtration rate than creatinine. On the other hand, low concentration of Cystatin C presents a risk factor for secondary cardiovascular events.Synonyms: CST3, Cystatin C, Cystatin-3, Gamma-trace, Neuroendocrine basic polypeptide, Post-gamma-globulin

Gen-ID: 1471

NCBI Accession: NP_000090

UniProt: P01034