Ezrin Antikörper (AA 362-585)
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- Target Alle Ezrin (EZR) Antikörper anzeigen
- Ezrin (EZR)
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Bindungsspezifität
- AA 362-585
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hamster, Känguruh
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Ezrin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
- Spezifität
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This antibody reacts with a protein of 81 kDa.
Cellular Localization: Cell membrane - Aufreinigung
- Purified
- Immunogen
- BALB/C mice were immunized with a recombinant fragment of human ezrin corresponding to amino acid 362-585.
- Klon
- 3C12
- Isotyp
- IgG1
- Top Product
- Discover our top product EZR Primärantikörper
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- Applikationshinweise
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Immunoprecipitation. Western blot: 1: 100-750. Immunohistochemistry on paraffin embedded sections: dilute 1: 50-1: 100 in an ABC method(30 minutes at room temperature). Recommended positive control: Lung.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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Knockdown of ezrin causes intrahepatic cholestasis by the dysregulation of bile fluidity in the bile duct epithelium in mice." in: Hepatology (Baltimore, Md.), Vol. 61, Issue 5, pp. 1660-71, (2015) (PubMed).
: "Polarization and migration of hematopoietic stem and progenitor cells rely on the RhoA/ROCK I pathway and an active reorganization of the microtubule network." in: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31661-71, (2010) (PubMed).
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Knockdown of ezrin causes intrahepatic cholestasis by the dysregulation of bile fluidity in the bile duct epithelium in mice." in: Hepatology (Baltimore, Md.), Vol. 61, Issue 5, pp. 1660-71, (2015) (PubMed).
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- Target
- Ezrin (EZR)
- Andere Bezeichnung
- Ezrin (EZR Produkte)
- Synonyme
- CVIL antikoerper, CVL antikoerper, VIL2 antikoerper, ezr antikoerper, vil2 antikoerper, wu:fc05c03 antikoerper, wu:fj31d06 antikoerper, cvil antikoerper, cvl antikoerper, Vil2 antikoerper, AW146364 antikoerper, R75297 antikoerper, p81 antikoerper, ezr.S antikoerper, ezrin antikoerper, ezrin b antikoerper, ezrin L homeolog antikoerper, EZR antikoerper, ezrb antikoerper, ezr antikoerper, Ezr antikoerper, ezr.L antikoerper
- Hintergrund
- Ezrin serves as a tyrosine kinase substrate and is phosphorylated in EGF-stimulated cells. Ezrin is a cytoplasmic protein enriched in microvilli and other cell surfaces. Ezrin has an actin-binding capacity. Ezrin is expressed in epithelial cells but not in mesenchymal cells. Ezrin is also expressed by certain epithelial tumors, such as renal cell adenocarcinomas.Synonyms: Cytovillin, EZR, VIL2, Villin-2, p81
- Gen-ID
- 7430
- NCBI Accession
- NP_001104547
- UniProt
- P15311
- Pathways
- Maintenance of Protein Location
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