CCL7 Antikörper

Produktnummer ABIN114719

Der Maus-Monoklonal Anti-CCL7-Antikörper wurde für WB und EIA validiert. Er ist geeignet zum Nachweis von CCL7 in Proben aus Human. }

Kurzübersicht für CCL7 Antikörper (ABIN114719)

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CCL7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: 542

Produktdetails anti-CCL7 Antikörper

Spezifität: Reactive with natural and recombinant Human MCP-3. Does not show any cross reaction with other Human Cytokines or growth factors tested such as IL1 beta, IL-8, MCAF, SAA and EGF.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: Recombinant human MCP-3 (M.W. 8.5 kDa containing 76 amino acids residues)

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA: CCL7 antibody can be used as a Capture antibody in Sandwich ELISA applicationsfor Human MCP-3 Detection in combination with a monoclonal tracer/detection antibody. Suggested Capture Coating Dose: 3 μg/well. Substrate: TMB. Western Blot: An antibody concentration of 0.5-2 μg/mL will allow visualization of 0.1 μg/lane of Human MCP-3.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with Double distillated to adjust the final concentration to 1.00 mg/mL

Buffer: 0.01 M PBS, pH 7.2 without preservatives

Konservierungsmittel: Without preservative

Handhabung: This product is photosensitive and should be protected from light

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C. DO NOT FREEZE!

Details zu CCL7

Target: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Andere Bezeichnung: MCP3 / CCL7

Hintergrund: Macrophage/monocyte chemotactic protein-3 (MCP-3), like other two closely related chemokines (MCP1 and MCP-2), is chemotactic to monocytes, but not to neutrophils. MCP-3 showed 78 % sequence homology with MCP-1 and 58 % sequence homology with MCP-2. The primary receptor for MCP-3 is D6. MCP-3 also competes with MCP-1 to bind to CCR10, and competes with Rantes and MIP-1α to bind to CCR1. MCP-3 stimulates macrophage to secrete proteases. A variety of cancer cell lines express MCP-3, suggesting a role in tumor invasion and metastasia.Synonyms: C-C motif chemokine 7, CCL-7, MCP-3, Macrophage Chemotactic Protein-3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7

Gen-ID: 6354

NCBI Accession: NP_006264

UniProt: P80098