ACP5 Antikörper

Produktnummer ABIN114707

Der Maus Monoklonal Anti-ACP5-Antikörper wurde für EIA validiert. Er ist geeignet, ACP5 in Proben von Human zu detektieren.

Kurzübersicht für ACP5 Antikörper (ABIN114707)

Target: ACP5 (Acid Phosphatase 5, Tartrate Resistant (ACP5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ACP5 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Klon: TRAP-01

Produktdetails anti-ACP5 Antikörper

Spezifität: The Anti Human TRAP 5 Antibody, Clone: TRAP-01 is a mouse monoclonal antibody against TRAP 5.

Aufreinigung: Affinity chromatography on protein G

Immunogen: Recombinant human TRAP 5 expressed in Sf 9 cells.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Enzyme Immunoassay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1 mL of deionized water and let the lyophilized pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.

Konzentration: 1.0 mg/mL

Buffer: 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE, None

Konservierungsmittel: Azide free

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.

Haltbarkeit: 6 months

Details zu ACP5

Target: ACP5 (Acid Phosphatase 5, Tartrate Resistant (ACP5))

Andere Bezeichnung: ACP5 / TR-AP

Hintergrund: TRAP 5 (serum band 5 tartrate-resistant acid phosphatase, TRACP 5, EC 3.1.3.2) is a glycoprotein of 35-37 kDa. TRAP 5 belongs to the most abundant enzymes in osteoclasts. It is expressed in certain differentiated cells of the mononuclear phagocyte system, particularly osteoclasts and alveolar macrophages, where it takes an active part in bone resorption process. High blood levels of TRAP 5 are usually associated with active bone remodelling. Increased serum levels are observed during normal bone growth among healthy children. Elevated serum TRAP levels have been detected in diseases characterized by increased bone resorption, Pagets disease of the bone, hemodialysis, primary hyperparathyroidism, metastatic malignancies involving bone resorption, multiple myeloma and bilaterally ovariectomized women. Post-menopausal women have higher levels of serum than post-menopausal women on estrogen replacement therapy. Therefore specific determination of TRAP 5 activity can be essential for clinical assessment of bone metabolism.Synonyms: Acid phosphatase 5 tartrate resistant, TRAP5, TRAcP, Tartrate-resistant acid ATPase, Tartrate-resistant acid phosphatase type 5

Gen-ID: 54

NCBI Accession: NP_001104504

UniProt: P13686

Pathways: Transition Metal Ion Homeostasis