KRT20 Antikörper

Produktnummer ABIN114613

Dieses Maus Monoklonal-Antikörper erkennt spezifisch KRT20 in IHC (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für KRT20 Antikörper (ABIN114613)

Target: KRT20 (Keratin 20 (KRT20))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KRT20 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: Ks20-8

Produktdetails anti-KRT20 Antikörper

Spezifität: This antibody reacts with cytokeratin polypeptide of 46 kDa in immunoblott analyses.
Cellular Localization: Cytoplasmic.

Aufreinigung: Purified

Immunogen: Cytokeratins isolated from human micro dissected villi of human duodenal mucosa.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry on Paraffin Sections: Use a dilution of 1/25-1/50 in an ABC method(30 minutes at room temperature). Formalin fixed paraffin embedded tissue sectionsrequire high temperature antigen unmasking with 10 mM Citrate buffer, pH 6.0 prior toimmunostaining. Positive Control: Skin.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu KRT20

Target: KRT20 (Keratin 20 (KRT20))

Andere Bezeichnung: Cytokeratin 20

Hintergrund: Cytokeratin 20 is a 46 kDa intermediate filament protein whose expression is restricted primarily to gastric and intestinal epithelium, urothelium, and Merkel cells. This antibody is highly specific to cytokeratin 20 and shows no cross-reactivity with other IFPs. Cytokeratin 20 is a unique type I keratin that is expressed in adenocarcinomas of the colon stomach, pancreas and bile system. It is also expressed in mucinous ovarian tumors, transitional cell carcinomas of the urinary tract, and Merkel cell carcinomas. This antibody is essentially non-reactive in squamous cell carcinomas and adenocarcinomas of the breast, lung, and endometrium, non-mucinous tumors of the ovary, and small cell carcinomas. This antibody is often used in conjunction with CK7 and other antibodies to distinguishing colon carcinomas (CK20+), from ovarian, pulmonary, and breast carcinomas.Synonyms: CK20, Cytokeratin 20, K20, KRT20, Keratin type I cytoskeletal 20, Keratin-20, Protein IT

Gen-ID: 54474

NCBI Accession: NP_061883

UniProt: P35900