IL16 Antikörper

Produktnummer ABIN114536

Der Maus Monoklonal anti-IL16 Antikörper wird verwendet zum Nachweis von IL16 in Proben von Human. Er wurde validiert für WB und EIA.

Kurzübersicht für IL16 Antikörper (ABIN114536)

Target: IL16 (Interleukin 16 (IL16))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Klon: 398

Produktdetails anti-IL16 Antikörper

Spezifität: Reactive with natural and recombinant Human IL-16. This monoclonal antibody exhibits no detectable cross-reacting with Human Albumin Serum, Bovine Albumin Serum and other Human cytokines or growth factors tested such as IL-1beta, IL-8, IL-7 MCAF, TGF-beta1, EGF, bFGF, GM-CSF, M-CSF, TNF-alpha.

Aufreinigung: Protein G affinity purified

Immunogen: Purified recombinant human IL-16

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: This antibody can be used as a capture antibody in sandwich ELISA applications forhuman IL-16 detection in combination with a monoclonal tracer/detection antibody. Suggested Capture Coating Dose: 0.3g/well, Substrate: TMB. If the above suggested conditions are followed, approximately 20pg/mL of IL-16 inserum/plasma or 15 pg/mL of IL-16 in cell medium/urine can be detected with an assayrange of 0-1000 pg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with Double distillated water is recommended and to adjust the final concentration to 1.0 mg/mL

Buffer: 0.01 M PBS, pH 7.2

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C. Do not freeze.

Details zu IL16

Target: IL16 (Interleukin 16 (IL16))

Andere Bezeichnung: Interleukin-16 / IL16

Hintergrund: IL16 is a proinflammatory cytokine that is chemotactic for CD4+ T lymphocytes, monocytes, and eosinophils. IL16 is synthesized as a precursor molecule (pro IL16) of approximately 68 kDa and 631 amino acid residues lacking a signal peptide. The sequence and structure of IL16 is conserved across species. In addition to inducing chemotaxis, IL16 upregulates the IL2 receptor and upregulates HLADR expression. It also inhibits T cell receptor (TCR)/CD3 dependent activation, and suppresses HIV1 replication in vitro. Sources of IL16 include epithelial cells, mast cells, T lymphocytes (CD4+ and CD8+), macrophages, synovial fibroblasts, and eosinophils.Synonyms: IL-16, LCF, Lymphocyte chemoattractant factor

Gen-ID: 3603

NCBI Accession: NP_001165599

UniProt: Q14005