NPY1R Antikörper (AA 365-378)
Kurzübersicht für NPY1R Antikörper (AA 365-378) (ABIN113620)
Target
Alle NPY1R Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 365-378
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Spezifität
- This antibody reacts with Neuropeptide Y Receptor 1.
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Aufreinigung
- Ammonium Sulphate Fractionation
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Immunogen
- Synthetic peptide corresponding to amino acids 365-378 of human NPY1R (KQASPVAFKKINNN) conjugated to KLH.
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Applikationshinweise
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ELISA. Western blot (1/250 as a guide). Immunohistochemistry on Paraffin Sections (1/1,000-1/4,000): See below for protocol.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Protokoll
- Protocol: - Samples: Bouin's fixed paraffin sections, 5 µm, from rat brain. - 5 minutes microwave pre-treatment, citrate buffer, pH 6. 0. - Peroxidase blocking (15 minutes), normal rabbit serum (30 minutes),
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 5.0 mg/mL
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Buffer
- PBS, pH 7.2, containing 0.09 % Sodium Azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- Do Not Add Sodium Azide
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Do not freeze working dilutions
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- NPY1R (Neuropeptide Y Receptor 1 (NPY1R))
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Andere Bezeichnung
- Neuropeptide Y Receptor 1
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Hintergrund
- Neuropeptide Y (NPY) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. There are two major subtypes of NPY (Y1 and Y2). The NPY Y1 receptors have been identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, breast, colon, ganglion, heart, and aortic smooth muscle. The Y2 receptor is found mainly in the central nervous system. NPY receptors are a member of the G protein-coupled receptor superfamily.Synonyms: NPYR, NPYY1, Neuropeptide Y receptor 1
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Gen-ID
- 4886
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NCBI Accession
- NP_000900
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UniProt
- P25929
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Pathways
- Feeding Behaviour
Target
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