Myoglobin Antikörper

Produktnummer ABIN113128

Dieses Ziege Polyklonal-Antikörper erkennt spezifisch Myoglobin in EIA und ELISA (Detection). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Myoglobin Antikörper (ABIN113128)

Target: Myoglobin (MB)

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Myoglobin Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), ELISA (Detection)

Produktdetails anti-Myoglobin Antikörper

Spezifität: Reacts with cardiac and skeletal forms of myoglobin.

Aufreinigung: Affinitty chromatography using immobilized human myoglobin

Reinheit: > 95 % pure

Immunogen: Highly purified human cardiac myoglobin

Anwendungsinformationen

Applikationshinweise: Immunoassays for human myoglobin
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 9.25 mg/mL (OD280nm, E1% = 13)

Buffer: 10 mM sodium phosphate and 0.85 % (w/v) sodium chloride, pH 7.2, containing 0.05 % sodium azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Myoglobin

Target: Myoglobin (MB)

Andere Bezeichnung: Myoglobin

Hintergrund: Myoglobin is a small heme containing protein (153 amino acid residues, molecular weight (w/o heme) 17053 Da and theoretical pI=7.29) responsible for the oxygen deposition in muscle tissues. Only one form of myoglobin is expressed in cardiac and skeletal muscles. Myoglobin is known as a marker of myocardial damage and it has been used for more than three decades. Nowadays it still is very commonly used in clinical practice as an early marker of AMI. It appears in patient's blood 1 to 3 hours after onset of the symptoms, reaching peak level within 8 to 12 hours. Myoglobin is not so cardiac specific as cTnI or cTnT. Because of high myoglobin concentration in skeletal muscle tissue, even minor skeletal muscle injury results in the significant increase of myoglobin concentration in blood. Thus myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.Synonyms: MB

Gen-ID: 4151

NCBI Accession: NP_005359

UniProt: P02144

Pathways: Brown Fat Cell Differentiation