CX3CR1 Antikörper (N-Term)

Produktnummer ABIN113101

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CX3CR1 in WB, FACS und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für CX3CR1 Antikörper (N-Term) (ABIN113101)

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CX3CR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CX3CR1 Antikörper

Bindungsspezifität: AA 2-21, N-Term

Spezifität: The antibody recognizes CX3CR1, N-terminal V28

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse and Rat.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Peptide corresponding to amino acids 2-21 of Human CX3CR1 Remarks: The sequence differs from those of Mouse and Rat CX3CR1 by four amino acids (3, 4).

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (2 μg/mL). Flow Cytometry. Western blot (1/500-1/2,000). Human spleen tissue lysate can be used as positive control and approx. 50 kDa band can bedetected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS with 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu CX3CR1

Target: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Andere Bezeichnung: CX3CR1 / GPR13

Hintergrund: CX3CR1 is one of the chemokine receptors that are required as co-receptors for HIV infection. The genes encoding Human, Mouse, and Rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion and has been implicated in tumor metastasis. CX3CR1 is expressed in a variety of human tissues and cell lines.Synonyms: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28

Gen-ID: 1524

NCBI Accession: NP_001164642

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin