Lactoferrin Antikörper (HRP)

Produktnummer ABIN113035

Produktdetails anti-Lactoferrin Antikörper (HRP)

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lactoferrin Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Aufreinigung: Immunoaffinity chromatography using antigens coupled to agarose beads.

Immunogen: Lactoferrin purified from human colostrum.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (1: 500 - 1: 5,000) on tissue sections.1: 5,000 - 1: 100,000 for ELISA and Western blotting with chromogenic substrates and1: 10,000 - 1: 200,000 for Western blotting with ECL substrates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with 1.5 mL distilled water. Centrifuge product if it is not completely clear after standing for 1-2 hours at room temperature.

Konzentration: 0.8 mg/mL (prior to lyophilization)

Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.6, containing 15 mg/mL BSA (IgG and Protease free)

Konservierungsmittel: Azide free

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2 - 8 °C.

Details zu Lactoferrin

Target: Lactoferrin (LTF) (Lactotransferrin (LTF))

Andere Bezeichnung: Lactotransferrin (LTF Produkte)

Synonyme: LTF antikoerper, GIG12 antikoerper, HLF2 antikoerper, LF antikoerper, Lf antikoerper, Csp82 antikoerper, MMS10R antikoerper, Ms10r antikoerper, PLF antikoerper, TFEW antikoerper, conalbumin antikoerper, lactotransferrin antikoerper, transferrin antikoerper, transferrin (ovotransferrin) antikoerper, LTF antikoerper, CpipJ_CPIJ000114 antikoerper, TF antikoerper, Ltf antikoerper

Hintergrund: Lactoferrin belongs to a family of iron-binding proteins that modulate iron metabolism, hemopoiesis, and immunologic reactions, together with transferrin and melanoma tumor antigen p97. They are evolutionary products of gene duplication and all 3 are encoded by genes on 3q. Lactoferrin is an iron binding glycoprotein with an approximate molecular weight of 80 kDa. The protein has two iron binding domains each housing one Fe3+ and the synergistic CO32- ion. The crystal structure form of human lactoferrin at 2.2A resolution exhibits 5330 protein atoms, 2Fe2+, 2CO32- and 98 carbohydrate atoms. Lactoferrin is absorbed from intestine by apical side of the membrane and localized to the nuclei. Intravenous infusion of lactoferrin is protective against lethal doses of E coli and induce bacterimia by a mechanism that downregulates neutrophil TNF alfa secretion. Recombinant human lactoferrin (rhLF), expressed and extracted from rice seed, is being evaluated for use as a dietary supplement to treat iron deficiency and/or iron deficiency induced anemia. Lactoferrin has been shown to have a role in the immune system and in early development of the embryo. A specific receptor for lactoferrin binding has been implicated in the human fetal intestine. Early embryonic localisation of lactoferrin by IHC has suggested its presence in various tissues including intestinal epitheliuem, kiney, and various regions of the brain.Synonyms: EC=3.4.21, LF, LTF, Lactoferrin, Talalactoferrin

Gen-ID: 9606

UniProt: P02788

Pathways: Transition Metal Ion Homeostasis