HBsAg
Reaktivität: Human
ELISA, LF
Wirt: Maus
Monoclonal
B-65
unconjugated
F(ab')2 fragment
Applikationshinweise
Suitable for use in ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1-2 mg/mL (OD280 nm, E0.1% = 1.4)
Buffer
PBS containing 10 mg/mL BSA as stabilizer and 0.002 % Thimerosal as preservative.
Konservierungsmittel
Thimerosal (Merthiolate)
Vorsichtsmaßnahmen
This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target
HBSAg (HBsAg)
(Hepatitis B Virus Surface Antigen (HBsAg))
Andere Bezeichnung
Hepatitis B Surface Antigen / HBsAg
Substanzklasse
Viral Protein
Hintergrund
Hepatitis B Virus (HBV) infection induces a disease state which manifests itself in a variety of ways, characterized by the extent of liver damage, inflammation and viral persistence. HBV infection is also associated with a 100 fold increased risk of hepatocellular carcinoma and currently infects over 250 million people worldwide. HBV has a partially double stranded 3.2 kilobase DNA genome which contains four open reading frames. One of these encodes a 154 amino acid protein called the HBx protein. HBx has been shown to be a transcriptional transactivator of both viral and cellular promoters. Lacking a DNA binding domain and nuclear localization signal, HBx is believed to exert transcriptional activity through protein protein interaction.Synonyms: HBV surface antigen, Hepatitis B Virus