CHRM3 Antikörper (AA 580-589)
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- Target Alle CHRM3 Antikörper anzeigen
- CHRM3 (Cholinergic Receptor, Muscarinic 3 (CHRM3))
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Bindungsspezifität
- AA 580-589
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Reaktivität
- Human, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CHRM3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- Specific for the C-term of the M3 receptor (580-589): 100 % . Crossreactivity to full receptor 70 %, M1 (451-460), M2 (457-466), M4 (469-478) and M5 (519-531) < 0.01 %.
- Immunogen
- Synthetic peptide M3 (580-589) covalently attached to a carrier protein.
- Top Product
- Discover our top product CHRM3 Primärantikörper
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- Applikationshinweise
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Immunocytochemical: this product has been found to stain PLP fixed rat brain sectionsknown to express the muscarinic M3 receptor using ABC techniques at a dilution of1: 2,500. Western immunoblotting: successful by using whole rat brain homogenerate at a dilutionof 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Rekonstitution
- Restore with 0.1 mL PBS containing 10 mg/mL BSA or with additional buffer for more dilute antibody.
- Konservierungsmittel
- Azide free
- Vorsichtsmaßnahmen
- Do Not Use Sodium Azide as preservative.
- Handhabung
- Avoid repeated freezing and thawing. Dilute only prior to immediate use
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store vial at 2-8 °C prior to restoration. For extended storage add glycerol to 50% and then aliquot contents and freeze at -20 °C or below. Centrifuge product if not completely clear after standing at room temperature. This antibody is stable for one month at 2-8 °C as an undiluted liquid.
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- Target
- CHRM3 (Cholinergic Receptor, Muscarinic 3 (CHRM3))
- Andere Bezeichnung
- Muscarinic Acetylcholine Receptor M3 (CHRM3 Produkte)
- Synonyme
- EGBRS antikoerper, HM3 antikoerper, MACHR antikoerper, Chrm-3 antikoerper, M3 antikoerper, M3R antikoerper, cholinergic receptor muscarinic 3 antikoerper, cholinergic receptor, muscarinic 3 antikoerper, cholinergic receptor, muscarinic 3, cardiac antikoerper, CHRM3 antikoerper, Chrm3 antikoerper
- Hintergrund
- This receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Expression of this receptor has been reported in brain, eye, and heart. ESTs have been isolated from brain, colon, fetus, lung, and prostate libraries.Synonyms: CHRM3
- Gen-ID
- 1131
- NCBI Accession
- NP_000731
- UniProt
- P20309
- Pathways
- Synaptic Membrane
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