Tetanus Toxin Antikörper (AA 1300-1314)
Kurzübersicht für Tetanus Toxin Antikörper (AA 1300-1314) (ABIN112840)
Target
Alle Tetanus Toxin (TetX) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1300-1314
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Spezifität
- This antibody detects Tetanus Toxin.
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Aufreinigung
- Affinity Chromatography on Protein A.
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Immunogen
- Synthetic peptide corresponding to the amino acids 1300-1314 of the native molecule conjugated to Keyhole limpet Haemocyanin.
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Applikationshinweise
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ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.1 mg/mL
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Buffer
- PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Tetanus Toxin (TetX)
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Andere Bezeichnung
- Tetanus Toxin
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Substanzklasse
- Bacteria
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Hintergrund
- Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.Synonyms: Clostridium tetani toxin, tetX
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Gen-ID
- 1061100
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NCBI Accession
- NP_783831
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UniProt
- P04958
Target
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