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Tetanus Toxin Antikörper (AA 1300-1314)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Tetanus Toxin in EIA. Er zeigt eine Reaktivität gegenüber Clostridium tetani.
Produktnummer ABIN112840

Kurzübersicht für Tetanus Toxin Antikörper (AA 1300-1314) (ABIN112840)

Target

Alle Tetanus Toxin (TetX) Antikörper anzeigen
Tetanus Toxin (TetX)

Reaktivität

Clostridium tetani

Wirt

  • 7
  • 4
  • 3
Kaninchen

Klonalität

  • 9
  • 4
Polyklonal

Konjugat

  • 14
Dieser Tetanus Toxin Antikörper ist unkonjugiert

Applikation

  • 6
  • 6
  • 4
  • 2
  • 2
  • 1
  • 1
Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 2
    • 1
    AA 1300-1314

    Spezifität

    This antibody detects Tetanus Toxin.

    Aufreinigung

    Affinity Chromatography on Protein A.

    Immunogen

    Synthetic peptide corresponding to the amino acids 1300-1314 of the native molecule conjugated to Keyhole limpet Haemocyanin.
  • Applikationshinweise

    ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.1 mg/mL

    Buffer

    PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target

    Tetanus Toxin (TetX)

    Andere Bezeichnung

    Tetanus Toxin

    Substanzklasse

    Bacteria

    Hintergrund

    Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.Synonyms: Clostridium tetani toxin, tetX

    Gen-ID

    1061100

    NCBI Accession

    NP_783831

    UniProt

    P04958
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