FOLR1 Antikörper

Produktnummer ABIN112586

Der Maus Monoklonal Anti-FOLR1-Antikörper wurde für EIA validiert. Er ist geeignet, FOLR1 in Proben von Human zu detektieren.

Kurzübersicht für FOLR1 Antikörper (ABIN112586)

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FOLR1 Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Klon: 1210-75

Produktdetails anti-FOLR1 Antikörper

Spezifität: This antibody is specific for folate binding protein isolated from milk. Cross reactivity with folate binding proteins from other sources has not been determined. Soluble folate binding protein from milk serves to accumulate and stabilize reduced folate compounds in the milk and aid in the absorbtion of folates by the intestinal mucosa of neonates.

Aufreinigung: Protein A chromatography

Immunogen: Purified Folate Binding Protein from bovine milk.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 2.4 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu FOLR1

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Andere Bezeichnung: Folate Receptor alpha

Hintergrund: Folate Binding Protein, has a high affinity for folic acid and for several reduced folic acid derivatives and mediates delivery of 5 methyltetrahydrofolate to the interior of cells. Membrane bound and soluble forms of a high affinity folate binding protein have been found in kidney, placenta, serum, milk, and in several cell lines. The 2 forms have similar binding characteristics for folates, are immunologically crossreactive, and, based upon limited amino acid sequence data, are nearly identical. There may be a precursor product relationship between the membrane and soluble forms, the membrane form having additional amino acid residues and greater molecular weight. The membrane form has been shown to mediate the transport of folate in cells grown in physiologic concentrations of folate. A function for the soluble form, which is found in serum, milk, and urine, has not been identified.Synonyms: Adult folate-binding protein, FOLR, FOLR1, FR-alpha, Folate receptor 1, KB cells FBP, MOv18, Ovarian tumor-associated antigen MOv18

Gen-ID: 2348

NCBI Accession: NP_000793

UniProt: P15328

Pathways: Dicarboxylic Acid Transport