ITGA3 Antikörper (Isoform 3B, N-Term)

Produktnummer ABIN112371

Dieses Anti-ITGA3-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ITGA3 in WB, IF und IHC (fro). Geeignet für Human.

Kurzübersicht für ITGA3 Antikörper (Isoform 3B, N-Term) (ABIN112371)

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 54B3

Produktdetails anti-ITGA3 Antikörper

Bindungsspezifität: Isoform 3B, N-Term

Sequenz: CTRYYQIMPK YHAVRIREEE RYPPPGSTLP TKK

Spezifität: 54B3 recognizes specifically the cytoplasmic domain of integrin subunit a3B which is present in microvascular structures in brain and heart.

Aufreinigung: Purified

Immunogen: Synthetic peptide corresponding to a 32 amino acid stretch in the cytoplasmic domain of integrin alpha3B including an appending N-terminal cysteine coupled to keyhole limpet hemocyanin.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Immunoblotting (1: 100 - 1: 1000). Immunocytochemistry. Immunohistochemistry on frozen tissues (1: 25 - 1: 200, with avidin-biotinylated horseradishperoxidase complex (ABC) as detection reagent).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu ITGA3

Target: ITGA3 (Integrin, alpha 3 (ITGA3))

Andere Bezeichnung: CD49c / ITGA3

Hintergrund: Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated α and β subunits. More than 18 α and 8 β subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. For integrin subunits α3 and α6, two cytoplasmic variants, A and B, have been identified.Synonyms: CD49 antigen-like family member C, FRP-2, GAPB3, Galactoprotein B3, ITGA-3, ITGAG3, Integrin alpha-3, MSK18, VLA-3 alpha chain, VLA3

Gen-ID: 3675

NCBI Accession: NP_002195

UniProt: P26006

Pathways: CXCR4-mediated Signaling Events, Integrin Complex