Ferritin Antikörper (Heavy & Light Chain)

Produktnummer ABIN112019

Der Maus Monoklonal Anti-Ferritin-Antikörper wurde für EIA validiert. Er ist geeignet, Ferritin in Proben von Human zu detektieren.

Kurzübersicht für Ferritin Antikörper (Heavy & Light Chain) (ABIN112019)

Target: Ferritin (FE)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ferritin Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Klon: 7A4

Produktdetails anti-Ferritin Antikörper

Bindungsspezifität: Heavy & Light Chain

Aufreinigung: Affinity chromatography on Protein G

Immunogen: Human liver ferritin.

Isotyp: IgG3

Anwendungsinformationen

Applikationshinweise: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Ferritin

Target: Ferritin (FE)

Andere Bezeichnung: Ferritin

Hintergrund: Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis by sequestering and storing iron in a non-toxic and soluble form. It forms a holoenzyme of ~450 kDa, consisting of 24 subunits of two types, H (heavy, 21 kDa) and L (light, 19 kDa), and is capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiological status of the cell, the ratio of H to L subunits in ferritin can vary widely. Ferritin is found in the liver, spleen, kidney and heart, with smaller amounts being found in blood. Serum ferritin levels serve as an indicator of the amount of iron stored in the body. Serum ferritin is the most sensitive test for anaemia, and is also used as a marker for restless leg syndrome, hemochromatosis and porphyria. As ferritin is an acute-phase reactant, it is often elevated during infection. Defects in ferritin proteins are associated with several neurodegenerative diseases.Synonyms: FTH, FTL, Ferritin H subunit, Ferritin L subunit

Pathways: Transition Metal Ion Homeostasis