CD68 Antikörper (FITC)

Produktnummer ABIN112006

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD68 in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CD68 Antikörper (FITC) (ABIN112006)

Target: CD68 (CD68 Molecule (CD68))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD68 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: Ki-M7

Produktdetails anti-CD68 Antikörper (FITC)

Spezifität: CD68 antibody BM4111F recognizes the 110KD integral membrane glycoprotein CD68 (Macrosialin) predominantly expressed on the intracellular lysosomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes.

Produktmerkmale: Absorption / Emission: 495 nm / 528 nm

Aufreinigung: Protein A Chromatography

Immunogen: Cell suspensions of Human lymph node

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Use 10 μL to label 10^6 cells in 100 μL (Membrane permeabilisation isrequired). Clone KiM7 has been reported as being also suitable for use in Immunoprecipitation andImmunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, 0.05 % Sodium Azide, 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu CD68

Target: CD68 (CD68 Molecule (CD68))

Andere Bezeichnung: CD68

Hintergrund: The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukaemia studies.Synonyms: Gp110, Macrophage marker, Macrosialin

Gen-ID: 968

NCBI Accession: NP_001035148

UniProt: P34810