CD68 Antikörper (PE)

Produktnummer ABIN111833

Der Maus Monoklonal Anti-CD68 Antikörper wurde für FACS validiert. Er ist geeignet, CD68 in Proben von Ratte zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für CD68 Antikörper (PE) (ABIN111833)

Target: CD68 (CD68 Molecule (CD68))

Reaktivität: Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD68 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Klon: ED1

Produktdetails anti-CD68 Antikörper (PE)

Spezifität: This antibody recognises CD68.

Aufreinigung: Affinity Chromatography on Protein A

Immunogen: Rat spleen cells. Spleen cells from immunised BALB/c mice were fused with cells of the SP2/0-Ag14 mouse myeloma cell line.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: Neat - 1/10, use 10 μL of the suggested working dilution to label 10^6 cellsin 100 μL, Results maybe enhanced using membrane permeabilisation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore with 1 mL distilled water

Buffer: PBS, 0.09 % Sodium Azide, 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Should this product contain a precipitate we recommend microcentrifugation before use.

Referenzen für anti-CD68 Antikörper (PE) (ABIN111833)

Schneider, Meusel, Renker, Bauer, Holzinger, Roeder, Wanner, Gekle, Sauvant: "Low-dose indomethacin after ischemic acute kidney injury prevents downregulation of Oat1/3 and improves renal outcome." in: American journal of physiology. Renal physiology, Vol. 297, Issue 6, pp. F1614-21, (2009) (PubMed).

Details zu CD68

Target: CD68 (CD68 Molecule (CD68))

Andere Bezeichnung: CD68

Hintergrund: The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.Synonyms: Gp110, Macrophage marker, Macrosialin

Gen-ID: 287435

NCBI Accession: NP_001026808

UniProt: Q4FZY1